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Liselot M Mus

Explore the profile of Liselot M Mus including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 723
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Recent Articles
1.
Bonine N, Zanzani V, Van Hemelryk A, Vanneste B, Zwicker C, Thone T, et al.
Cell Rep . 2024 Oct; 43(10):114804. PMID: 39368085
Neuroblastoma, a rare embryonic tumor arising from neural crest development, is responsible for 15% of pediatric cancer-related deaths. Recently, several single-cell transcriptome studies were performed on neuroblastoma patient samples to...
2.
Cornelli L, Van Paemel R, Ferro Dos Santos M, Roelandt S, Willems L, Vandersteene J, et al.
Clin Epigenetics . 2024 Jul; 16(1):87. PMID: 38970137
Pediatric central nervous system tumors remain challenging to diagnose. Imaging approaches do not provide sufficient detail to discriminate between different tumor types, while the histopathological examination of tumor tissue shows...
3.
Zanotti S, Vanhauwaert S, Van Neste C, Olexiouk V, Van Laere J, Verschuuren M, et al.
Sci Rep . 2021 Jul; 11(1):14454. PMID: 34262099
MYCN is an oncogenic driver in neural crest-derived neuroblastoma and medulloblastoma. To better understand the early effects of MYCN activation in a neural-crest lineage context, we profiled the transcriptome of...
4.
Mus L, Van Haver S, Popovic M, Trypsteen W, Lefever S, Zeltner N, et al.
Genes Chromosomes Cancer . 2020 Dec; 60(4):272-281. PMID: 33336840
Human embryonic stem cells (hESCs) and embryonal tumors share a number of common features, including a compromised G1/S checkpoint. Consequently, these rapidly dividing hESCs and cancer cells undergo elevated levels...
5.
Mus L, Lambertz I, Claeys S, Kumps C, Van Loocke W, Van Neste C, et al.
Sci Rep . 2020 Jan; 10(1):218. PMID: 31937834
Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an urgent need for novel targeted therapeutic approaches. Detailed molecular...
6.
Claeys S, Denecker G, Durinck K, Decaesteker B, Mus L, Loontiens S, et al.
Oncogene . 2018 Dec; 38(15):2690-2705. PMID: 30538293
ALK mutations occur in 10% of primary neuroblastomas and represent a major target for precision treatment. In combination with MYCN amplification, ALK mutations infer an ultra-high-risk phenotype resulting in very...
7.
Mus L, Denecker G, Speleman F, Roman B
PLoS One . 2018 Feb; 13(2):e0192548. PMID: 29470507
Effective inhibitors of invasion and metastasis represent a serious unmet clinical need. We have recently identified 4-fluoro-3',4',5'-trimethoxychalcone or C16 as a potent anti-invasive molecule. In this paper, we report on...
8.
Van Deun J, Mestdagh P, Agostinis P, Akay O, Anand S, Anckaert J, et al.
Nat Methods . 2017 Mar; 14(3):228-232. PMID: 28245209
We argue that the field of extracellular vesicle (EV) biology needs more transparent reporting to facilitate interpretation and replication of experiments. To achieve this, we describe EV-TRACK, a crowdsourcing knowledgebase...
9.
Van Goethem A, Yigit N, Everaert C, Moreno-Smith M, Mus L, Barbieri E, et al.
Sci Rep . 2016 Dec; 6:37876. PMID: 27901112
The ongoing ascent of sequencing technologies has enabled researchers to gain unprecedented insights into the RNA content of biological samples. MiRNAs, a class of small non-coding RNAs, play a pivotal...
10.
Bracke M, Roman B, Stevens C, Mus L, Parmar V, de Wever O, et al.
J Vis Exp . 2015 Jul; (100):e52792. PMID: 26131648
The goal of the chick heart assay is to offer a relevant organ culture method to study tumor invasion in three dimensions. The assay can distinguish between invasive and non-invasive...