Lisa T Mackenzie
Overview
Explore the profile of Lisa T Mackenzie including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
315
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Recent Articles
1.
Kirstein J, Graham K, Mackenzie L, Johnston D, Martin L, Tuck A, et al.
Clin Exp Metastasis
. 2008 Dec;
26(2):121-31.
PMID: 19082867
Anti-fibrinolytic agents such as aprotinin and epsilon-aminocaproic acid (EACA) are used clinically to decrease peri-operative bleeding. Use of these treatments during cancer-related surgeries has led to investigation of the effect...
2.
Ramadan S, Heyn C, Mackenzie L, Chambers A, Rutt B, Foster P
MAGMA
. 2008 Jun;
21(4):251-9.
PMID: 18581153
Introduction: The use of MRI with iron-based magnetic nanoparticles for imaging cells is a rapidly growing field of research. We have recently reported that single iron-labeled cells could be detected,...
3.
Graham K, Detombe S, Mackenzie L, Holdsworth D, MacDonald I, Chambers A, et al.
Invest Radiol
. 2008 Jun;
43(7):488-95.
PMID: 18580331
Objectives: To determine if intraperitoneally (IP) administered contrast (iohexol), used in conjunction with a liver-specific agent (Fenestra), can improve measurement precision and accuracy when quantifying tumor volume from micro-CT images...
4.
Graham K, Ford N, Mackenzie L, Postenka C, Groom A, MacDonald I, et al.
Invest Radiol
. 2008 Jan;
43(2):92-9.
PMID: 18197061
Objectives: To determine a timepoint after contrast injection that yields equal liver parenchymal and vascular enhancement in micro-computed tomography images. To evaluate the utility of images acquired during this time...
5.
Heyn C, Ronald J, Ramadan S, Snir J, Barry A, Mackenzie L, et al.
Magn Reson Med
. 2006 Oct;
56(5):1001-10.
PMID: 17029229
Metastasis (the spread of cancer from a primary tumor to secondary organs) is responsible for most cancer deaths. The ability to follow the fate of a population of tumor cells...
6.
Heyn C, Ronald J, Mackenzie L, MacDonald I, Chambers A, Rutt B, et al.
Magn Reson Med
. 2005 Dec;
55(1):23-9.
PMID: 16342157
In the current work we demonstrate, for the first time, that single cells can be detected in mouse brain in vivo using magnetic resonance imaging (MRI). Cells were labeled with...
7.
Graham K, Wirtzfeld L, Mackenzie L, Postenka C, Groom A, MacDonald I, et al.
Cancer Res
. 2005 Jun;
65(12):5231-7.
PMID: 15958568
Liver metastasis is a clinically significant contributor to the mortality associated with melanoma, colon, and breast cancer. Preclinical mouse models are essential to the study of liver metastasis, yet their...
8.
Varghese H, Mackenzie L, Groom A, Ellis C, Ryan A, MacDonald I, et al.
Angiogenesis
. 2004 Nov;
7(2):157-64.
PMID: 15516836
Metastases require a functional blood supply for progressive growth. Thus, therapies that target metastatic vasculature have potential clinical utility. The effects of the vascular-targeting agent (VTA), ZD6126, and the anti-angiogenic...
9.
Varghese H, Mackenzie L, Groom A, Ellis C, Chambers A, MacDonald I
Am J Physiol Heart Circ Physiol
. 2004 Sep;
288(1):H185-93.
PMID: 15388500
A functional microcirculation is vital to the survival of mammalian tissues. In vivo video microscopy is often used in animal models to assess microvascular function, providing real-time observation of blood...