Lisa Smeester
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Explore the profile of Lisa Smeester including associated specialties, affiliations and a list of published articles.
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59
Citations
1314
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Recent Articles
1.
Grace M, Vora N, Smeester L, Dotters-Katz S, Fry R, Bae-Jump V, et al.
Am J Perinatol
. 2023 Jan;
41(S 01):e1273-e1280.
PMID: 36608700
Objective: In utero fetal exposures may have sex-specific placental gene responses. Our objective was to measure sex-based differences in placental gene expression from dams fed high-fat diet (HFD) versus control...
2.
Bulka C, Eaves L, Gardner A, Parsons P, Galusha A, Roell K, et al.
Front Epidemiol
. 2022 Nov;
2.
PMID: 36405975
Background: Prenatal exposures to metallic and metalloid trace elements have been linked to altered immune function in animal studies, but few epidemiologic studies have investigated immunological effects in humans. We...
3.
Clark J, Bulka C, Martin C, Roell K, Santos H, OShea T, et al.
Epigenetics
. 2022 Sep;
17(13):2389-2403.
PMID: 36134874
Social determinants of health (SDoH) are defined as the conditions in which people are born, grow, live, work, and age. The distribution of these conditions is influenced by underlying structural...
4.
Freedman A, Eaves L, Rager J, Gavino-Lopez N, Smeester L, Bangma J, et al.
Epigenomics
. 2022 Sep;
14(15):897-911.
PMID: 36073148
The placenta-brain axis reflects a developmental linkage where disrupted placental function is associated with impaired neurodevelopment later in life. Placental gene expression and the expression of epigenetic modifiers such as...
5.
Eaves L, Enggasser A, Camerota M, Gogcu S, Gower W, Hartwell H, et al.
Pediatr Res
. 2022 Jun;
93(4):1072-1084.
PMID: 35764815
Background: Infants born extremely premature are at increased risk for health complications later in life for which neonatal inflammation may be a contributing biological driver. Placental CpG methylation provides mechanistic...
6.
Bhattacharya A, Freedman A, Avula V, Harris R, Liu W, Pan C, et al.
Nat Commun
. 2022 Feb;
13(1):706.
PMID: 35121757
As the master regulator in utero, the placenta is core to the Developmental Origins of Health and Disease (DOHaD) hypothesis but is historically understudied. To identify placental gene-trait associations (GTAs)...
7.
Jackson W, Santos Jr H, Hartwell H, Gower W, Chhabra D, Hagood J, et al.
Pediatr Res
. 2021 Dec;
91(6):1428-1435.
PMID: 34857876
Background: Chronic lung disease (CLD) is the most common pulmonary morbidity in extremely preterm infants. It is unclear to what extent prenatal exposures influence the risk of CLD. Epigenetic variation...
8.
Clark J, Eaves L, Gaona A, Santos Jr H, Smeester L, Bangma J, et al.
Sci Rep
. 2021 Aug;
11(1):15743.
PMID: 34344912
Pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and neonatal health outcomes, with differences in risk observed between sexes. Given that the placenta is a sexually dimorphic organ...
9.
Clark J, Avula V, Ring C, Eaves L, Howard T, Santos H, et al.
Toxicol Sci
. 2021 Jul;
183(2):269-284.
PMID: 34255065
Molecular signatures are being increasingly integrated into predictive biology applications. However, there are limited studies comparing the overall predictivity of transcriptomic versus epigenomic signatures in relation to perinatal outcomes. This...
10.
Oldenburg K, Eaves L, Smeester L, Santos H, OShea T, Fry R
Placenta
. 2021 Jun;
111:82-90.
PMID: 34182215
Introduction: Placental inflammation is associated with a variety of adverse health outcomes, including poor pregnancy outcomes as well as later in life health. The current clinical methodologies for evaluating placental...