Lisa Scandiuzzi
Overview
Explore the profile of Lisa Scandiuzzi including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
725
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0
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Recent Articles
1.
Garrett-Thomson S, Massimi A, Fedorov E, Bonanno J, Scandiuzzi L, Hillerich B, et al.
PLoS One
. 2020 Jun;
15(6):e0233578.
PMID: 32497097
The B7 family represents one of the best-studied subgroups within the Ig superfamily, yet new interactions continue to be discovered. However, this binding promiscuity represents a major challenge for defining...
2.
Lazar-Molnar E, Scandiuzzi L, Basu I, Quinn T, Sylvestre E, Palmieri E, et al.
EBioMedicine
. 2017 Feb;
17:30-44.
PMID: 28233730
Programmed Cell Death-1 (PD-1) is an inhibitory immune receptor, which plays critical roles in T cell co-inhibition and exhaustion upon binding to its ligands PD-L1 and PD-L2. We report the...
3.
Usman H, Ameer F, Munir R, Iqbal A, Zaid M, Hasnain S, et al.
Clin Chim Acta
. 2016 Mar;
457:12-7.
PMID: 27012514
Background: Different types of cancer cells are previously shown to accumulate intracellular cholesterol. However, the data on intracellular cholesterol levels in leukemia cells provide contradictory evidence. Various previous works indicate...
4.
Bandyopadhyay S, Quinn T, Scandiuzzi L, Basu I, Partanen A, Tome W, et al.
J Immunol
. 2016 Jan;
196(4):1964-76.
PMID: 26755821
Immune responses against cancer cells are often hindered by immunosuppressive mechanisms that are developed in the tumor microenvironment. Induction of a hyporesponsive state in tumor Ag-specific T cells is one...
5.
Iqbal A, Zaid M, Munir R, Usman H, Kalbacher H, Scandiuzzi L, et al.
Clin Chim Acta
. 2015 Nov;
452:129-33.
PMID: 26549657
Numerous studies have reported alterations in the plasma lipid profiles of leukemia patients. However, there are several inconsistencies in these reports. The present review highlights and compiles findings from different...
6.
Rashid R, Ameer F, Kalbacher H, Scandiuzzi L, Zaidi N
Clin Chim Acta
. 2015 Sep;
450:356-61.
PMID: 26386164
Human cells can acquire cholesterol from the circulation but also have the ability to synthesize it via de novo cholesterogenesis (DC). Cholesterol absorption and de novo cholesterogenesis are the key...
7.
Jeon H, Vigdorovich V, Garrett-Thomson S, Janakiram M, Ramagopal U, Abadi Y, et al.
Cell Rep
. 2014 Dec;
9(3):1089-98.
PMID: 25437562
B7x (B7-H4 or B7S1) is a member of the B7 family that can inhibit T cell function. B7x protein is absent in most normal human tissues and immune cells, but...
8.
Ameer F, Scandiuzzi L, Hasnain S, Kalbacher H, Zaidi N
Metabolism
. 2014 May;
63(7):895-902.
PMID: 24814684
Background: De novo lipogenesis (DNL) is a complex and highly regulated metabolic pathway. In normal conditions DNL converts excess carbohydrate into fatty acids that are then esterified to storage triacylglycerols...
9.
Scandiuzzi L, Ghosh K, Hofmeyer K, Abadi Y, Lazar-Molnar E, Lin E, et al.
Cell Rep
. 2014 Feb;
6(4):625-32.
PMID: 24529703
B7-H1 (PD-L1) on immune cells plays an important role in T cell coinhibition by binding its receptor PD-1. Here, we show that both human and mouse intestinal epithelium express B7-H1...
10.
Zhao R, Chinai J, Buhl S, Scandiuzzi L, Ray A, Jeon H, et al.
Proc Natl Acad Sci U S A
. 2013 May;
110(24):9879-84.
PMID: 23716685
T-cell costimulation and coinhibition generated by engagement of the B7 family and their receptor CD28 family are of central importance in regulating the T-cell response, making these pathways very attractive...