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Lisa Patrone

Explore the profile of Lisa Patrone including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 259
Followers 0
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Recent Articles
1.
Konkle B, Stasyshyn O, Chowdary P, Bevan D, Mant T, Shima M, et al.
Blood . 2015 Jul; 126(9):1078-85. PMID: 26157075
Current management of hemophilia A includes prophylaxis with factor VIII (FVIII) replacement every 2 to 3 days. BAX 855, Baxalta's pegylated full-length recombinant FVIII (rFVIII), was designed to increase half-life...
2.
Berntorp E, Spotts G, Patrone L, Ewenstein B
Biologics . 2014 Apr; 8:115-27. PMID: 24741292
Detailed analysis of data from studies of recombinant antihemophilic factor produced using a plasma/albumin-free method (rAHF-PFM) in previously treated patients showed a substantial level of interpatient variation in pharmacokinetics (PKs),...
3.
Shapiro A, Gruppo R, Pabinger I, Collins P, Hay C, Schroth P, et al.
Expert Opin Biol Ther . 2009 Feb; 9(3):273-83. PMID: 19216617
Background: Hemophilia A is an X-linked bleeding disorder that results from insufficient levels of factor VIII (FVIII) coagulant activity. Objective: To evaluate the efficacy and safety of ADVATE rAHF-PFM (Baxter...
4.
Church J, Leibl H, Stein M, Melamed I, Rubinstein A, Schneider L, et al.
J Clin Immunol . 2006 May; 26(4):388-95. PMID: 16705486
The present clinical study was designed to evaluate the efficacy, pharmacokinetics and safety of a new 10% liquid intravenous immune globulin in patients with primary immunodeficiency diseases. Sixty-one adults and...
5.
Patrone L, Henson S, Wall R, Malone C
Mol Biol Rep . 2004 Mar; 31(1):1-11. PMID: 15040449
The human, murine, and rat B29 (Ig beta, CD79b) genes are highly conserved in sequence and organization and exhibit strict B cell-specific expression. In the human and rat genomes, the...
6.
Patrone L, Henson S, Teodorovic J, Malone C, French S, Wall R, et al.
Exp Mol Pathol . 2003 Apr; 74(2):129-39. PMID: 12710944
Diffuse large B-cell lymphoma (DLBCL) is more prevalent and more often fatal in AIDS patients compared to immune-competent individuals. Potential explanations for these differences include distinct tumorigenic mechanisms and/or altered...
7.
Su T, Guo B, Kawakami Y, Sommer K, Chae K, Humphries L, et al.
Nat Immunol . 2002 Jul; 3(8):780-6. PMID: 12118249
NF-kappa B signaling is required for the maintenance of normal B lymphocytes, whereas dysregulated NF-kappa B activation contributes to B cell lymphomas. The events that regulate NF-kappa B signaling in...
8.
Patrone L, Damore M, Lee M, Malone C, Wall R
Mol Immunol . 2002 Jan; 38(8):597-606. PMID: 11792428
Interferon-gamma (IFN gamma) exerts diverse responses in B cell development ranging from growth arrest and apoptosis to proliferation and differentiation. IFN gamma stimulates murine 70Z/3 pre-B cells to express surface...