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Lisa McFerrin

Explore the profile of Lisa McFerrin including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 665
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Recent Articles
1.
Wirsching H, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino P, et al.
JCI Insight . 2019 Jul; 4(13). PMID: 31292299
Oncolytic viruses induce local tumor destruction and inflammation. Whether virotherapy can also overcome immunosuppression in noninfected tumor areas is under debate. To address this question, we have explored immunologic effects...
2.
Winters B, De Sarkar N, Arora S, Bolouri H, Jana S, Vakar-Lopez F, et al.
JCI Insight . 2019 May; 5. PMID: 31145100
Background: Little is known about the genomic differences between metastatic urothelial carcinoma (LTUC) and upper tract urothelial carcinoma (UTUC). We compare genomic features of primary and metastatic UTUC and LTUC...
3.
Cimino P, McFerrin L, Wirsching H, Arora S, Bolouri H, Rabadan R, et al.
Neuro Oncol . 2018 Jul; 20(10):1368-1373. PMID: 29982740
Background: Copy number alterations form prognostic molecular subtypes of glioblastoma with clear differences in median overall survival. In this study, we leverage molecular data from several glioblastoma cohorts to define...
4.
Cimino P, Zager M, McFerrin L, Wirsching H, Bolouri H, Hentschel B, et al.
Acta Neuropathol Commun . 2017 May; 5(1):39. PMID: 28532485
Recent updating of the World Health Organization (WHO) classification of central nervous system (CNS) tumors in 2016 demonstrates the first organized effort to restructure brain tumor classification by incorporating histomorphologic...
5.
Schliekelman M, Taguchi A, Zhu J, Dai X, Rodriguez J, Celiktas M, et al.
Cancer Res . 2015 Mar; 75(9):1789-800. PMID: 25744723
Epithelial-to-mesenchymal transition (EMT) is a key process associated with tumor progression and metastasis. To define molecular features associated with EMT states, we undertook an integrative approach combining mRNA, miRNA, DNA...
6.
Carroll P, Diolaiti D, McFerrin L, Gu H, Djukovic D, Du J, et al.
Cancer Cell . 2015 Feb; 27(2):271-85. PMID: 25640402
Deregulated Myc transcriptionally reprograms cell metabolism to promote neoplasia. Here we show that oncogenic Myc requires the Myc superfamily member MondoA, a nutrient-sensing transcription factor, for tumorigenesis. Knockdown of MondoA,...
7.
Diolaiti D, McFerrin L, Carroll P, Eisenman R
Biochim Biophys Acta . 2014 May; 1849(5):484-500. PMID: 24857747
The transcription factor MYC and its related family members MYCN and MYCL have been implicated in the etiology of a wide spectrum of human cancers. Compared to other oncoproteins, such...
8.
Conacci-Sorrell M, McFerrin L, Eisenman R
Cold Spring Harb Perspect Med . 2014 Jan; 4(1):a014357. PMID: 24384812
This review is intended to provide a broad outline of the biological and molecular functions of MYC as well as of the larger protein network within which MYC operates. We...