Lisa M Wittenhagen
Overview
Explore the profile of Lisa M Wittenhagen including associated specialties, affiliations and a list of published articles.
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7
Citations
112
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Recent Articles
1.
Wittenhagen L, Carreon J, Prestwich E, Kelley S
Angew Chem Int Ed Engl
. 2005 Mar;
44(17):2542-6.
PMID: 15770631
No abstract available.
2.
Roy M, Wittenhagen L, Kelley S
RNA
. 2005 Feb;
11(3):254-60.
PMID: 15701731
The A3243G mutation within the human mitochondrial (hs mt) tRNALeuUUR gene is associated with maternally inherited deafness and diabetes (MIDD) and other mitochondrial encephalopathies. One of the most pronounced structural...
3.
Carreon J, Roberts M, Wittenhagen L, Kelley S
Org Lett
. 2004 Dec;
7(1):99-102.
PMID: 15624987
Peptide conjugates of the xanthene dye rose bengal (RB) are described featuring sequences that promote DNA binding. The complexation of these conjugates with DNA causes efficient quenching of the fluorophore...
4.
Roy M, Wittenhagen L, Vozzella B, Kelley S
Biochemistry
. 2004 Jan;
43(2):384-92.
PMID: 14717592
The structure of the human mitochondrial (hs mt) tRNALeu(UUR) features several domains that are predicted to exhibit limited thermodynamic stability. An elevated frequency of disease-related mutations within these domains suggests...
5.
Wittenhagen L, Kelley S
Trends Biochem Sci
. 2003 Nov;
28(11):605-11.
PMID: 14607091
Over 150 mutations with documented pathogenicity have been identified within the human mitochondrial genome. More than half of the disease-related mutations are located within tRNA genes, a remarkable trend, given...
6.
Wittenhagen L, Roy M, Kelley S
Nucleic Acids Res
. 2003 Jan;
31(2):596-601.
PMID: 12527767
The U3271C mutation affecting the human mitochondrial transfer RNA(Leu(UUR)) (hs mt tRNA) is correlated with diabetes and mitochondrial encephalopathies. We have explored the relationship between the structural effects of this...
7.
Wittenhagen L, Kelley S
Nat Struct Biol
. 2002 Jul;
9(8):586-90.
PMID: 12101407
Mutations of human mitochondrial transfer RNA (tRNA) are implicated in a variety of multisystemic diseases. The most prevalent pathogenic mitochondrial mutation is the A3243G substitution within the gene for tRNA(Leu(UUR))....