Lisa L Kirkemo
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Explore the profile of Lisa L Kirkemo including associated specialties, affiliations and a list of published articles.
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15
Citations
138
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Recent Articles
1.
Mittl K, Hayashi F, Dandekar R, Schubert R, Gerdts J, Oshiro L, et al.
bioRxiv
. 2024 Sep;
PMID: 39282370
CD8+ T cells are the dominant lymphocyte population in multiple sclerosis (MS) lesions where they are highly clonally expanded. The clonal identity, function, and antigen specificity of CD8+ T cells...
2.
Delaveris C, Kong S, Glasgow J, Loudermilk R, Kirkemo L, Zhao F, et al.
Cell Chem Biol
. 2024 Aug;
31(9):1729-1739.e9.
PMID: 39178841
Foreign epitopes for immune recognition provide the basis of anticancer immunity. Due to the high concentration of extracellular adenosine triphosphate in the tumor microenvironment, we hypothesized that extracellular kinases (ectokinases)...
3.
Yang J, Wang L, Byrnes J, Kirkemo L, Driks H, Belair C, et al.
Cancer Immunol Res
. 2024 Apr;
12(5):575-591.
PMID: 38588410
Poliovirus receptor-related 2 (PVRL2, also known as nectin-2 or CD112) is believed to act as an immune checkpoint protein in cancer; however, most insight into its role is inferred from...
4.
Delaveris C, Kong S, Glasgow J, Loudermilk R, Kirkemo L, Zhao F, et al.
bioRxiv
. 2024 Apr;
PMID: 38562834
New epitopes for immune recognition provide the basis of anticancer immunity. Due to the high concentration of extracellular adenosine triphosphate in the tumor microenvironment, we hypothesized that extracellular kinases (ectokinases)...
5.
Bartholow T, Burroughs P, Elledge S, Byrnes J, Kirkemo L, Garda V, et al.
ACS Cent Sci
. 2024 Jan;
10(1):199-208.
PMID: 38292613
The cell surface proteome (surfaceome) plays a pivotal role in virtually all extracellular biology, and yet we are only beginning to understand the protein complexes formed in this crowded environment....
6.
Rettko N, Kirkemo L, Wells J
PNAS Nexus
. 2023 Dec;
2(12):pgad400.
PMID: 38099269
Human leukocyte antigens (HLA) present peptides largely from intracellular proteins on cell surfaces. As these complexes can serve as biomarkers in disease, proper identification of peptides derived from disease-associated antigens...
7.
Bartholow T, Burroughs P, Elledge S, Byrnes J, Kirkemo L, Garda V, et al.
bioRxiv
. 2023 Aug;
PMID: 37546992
The cell surface proteome, or surfaceome, is encoded by more than 4000 genes, but we are only beginning to understand the complexes they form. Rapid proximity labeling around specific membrane...
8.
Rettko N, Kirkemo L, Wells J
bioRxiv
. 2023 Apr;
PMID: 37090675
Human leukocyte antigens (HLA) display peptides largely from intracellular proteins on the surface of cells in major histocompatibility complex (MHC)-peptide complexes. These complexes provide a biological window into the cell,...
9.
Solomon P, Kirkemo L, Wilson G, Leung K, Almond M, Sayles L, et al.
Mol Cell Proteomics
. 2022 May;
21(7):100247.
PMID: 35594991
Since the discovery of oncogenes, there has been tremendous interest to understand their mechanistic basis and to develop broadly actionable therapeutics. Some of the most frequently activated oncogenes driving diverse...
10.
Kirkemo L, Elledge S, Yang J, Byrnes J, Glasgow J, Blelloch R, et al.
Elife
. 2022 Mar;
11.
PMID: 35257663
Characterization of cell surface proteome differences between cancer and healthy cells is a valuable approach for the identification of novel diagnostic and therapeutic targets. However, selective sampling of surface proteins...