Lisa J Strug
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Explore the profile of Lisa J Strug including associated specialties, affiliations and a list of published articles.
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96
Citations
2303
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Recent Articles
1.
Garg E, Arguello-Pascualli P, Vishnyakova O, Halevy A, Yoo S, Brooks J, et al.
PLoS Genet
. 2025 Mar;
21(3):e1011628.
PMID: 40036184
[This corrects the article DOI: 10.1371/journal.pgen.1011192.].
2.
Tadros R, Zheng S, Grace C, Jorda P, Francis C, West D, et al.
Nat Genet
. 2025 Feb;
57(3):530-538.
PMID: 39966646
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality with both monogenic and polygenic components. Here, we report results from a large genome-wide association study and multitrait analysis...
3.
Jad R, Ma X, Stanojevic S, Illango A, Tullis E, Gilmour J, et al.
J Bone Miner Res
. 2024 Sep;
39(12):1716-1721.
PMID: 39221749
Improved survival in people with cystic fibrosis (pwCF) presents new complexities of care, including CF-related bone disease, a common complication in older pwCF. The trajectory of bone loss with age...
4.
Lin B, Gong J, Keenan K, Lin F, Lin Y, Mesinele J, et al.
Eur Respir J
. 2024 Aug;
64(5).
PMID: 39117430
Background: is a common pathogen that contributes to progressive lung disease in cystic fibrosis (CF). Genetic factors other than CF-causing (CF transmembrane conductance regulator) variations contribute ∼85% of the variation...
5.
Slobodyanyuk M, Bahcheli A, Klein Z, Bayati M, Strug L, Reimand J
Nat Commun
. 2024 Jul;
15(1):5690.
PMID: 38971800
Omics techniques generate comprehensive profiles of biomolecules in cells and tissues. However, a holistic understanding of underlying systems requires joint analyses of multiple data modalities. We present DPM, a data...
6.
Agrawal S, Buyan A, Severin J, Koido M, Alam T, Abugessaisa I, et al.
PLoS One
. 2024 May;
19(5):e0295971.
PMID: 38709794
The human genome is pervasively transcribed and produces a wide variety of long non-coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types. Some specific nuclear lncRNAs have...
7.
Garg E, Arguello-Pascualli P, Vishnyakova O, Halevy A, Yoo S, Brooks J, et al.
PLoS Genet
. 2024 Mar;
20(3):e1011192.
PMID: 38517939
The HostSeq initiative recruited 10,059 Canadians infected with SARS-CoV-2 between March 2020 and March 2023, obtained clinical information on their disease experience and whole genome sequenced (WGS) their DNA. We...
8.
Roshandel D, Sanders E, Shakeshaft A, Panjwani N, Lin F, Collingwood A, et al.
NPJ Genom Med
. 2023 Sep;
8(1):28.
PMID: 37770509
Elevated impulsivity is a key component of attention-deficit hyperactivity disorder (ADHD), bipolar disorder and juvenile myoclonic epilepsy (JME). We performed a genome-wide association, colocalization, polygenic risk score, and pathway analysis...
9.
Rubboli G, Beier C, Selmer K, Syvertsen M, Shakeshaft A, Collingwood A, et al.
Brain Commun
. 2023 Jun;
5(3):fcad182.
PMID: 37361715
Reliable definitions, classifications and prognostic models are the cornerstones of stratified medicine, but none of the current classifications systems in epilepsy address prognostic or outcome issues. Although heterogeneity is widely...
10.
Zarrei M, Burton C, Engchuan W, Higginbotham E, Wei J, Shaikh S, et al.
Hum Mol Genet
. 2023 May;
32(15):2411-2421.
PMID: 37154571
We assessed the relationship of gene copy number variation (CNV) in mental health/neurodevelopmental traits and diagnoses, physical health and cognition in a community sample of 7100 unrelated children and youth...