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Lisa High Mitchell

Explore the profile of Lisa High Mitchell including associated specialties, affiliations and a list of published articles. Areas
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Citations 88
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Recent Articles
1.
Pyle L, Ehrhardt A, Mitchell L, Fan L, Ren A, Naren A, et al.
Am J Physiol Lung Cell Mol Physiol . 2011 Jul; 301(4):L587-97. PMID: 21724857
Modulator compounds intended to overcome disease-causing mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) show significant promise in clinical testing for cystic fibrosis. However, the mechanism(s) of action underlying...
2.
MacKenzie K, Topping E, Bugaj-Gaweda B, Deng C, Cheung Y, Olsen A, et al.
Biochem J . 2007 Dec; 411(2):361-9. PMID: 18095939
We have isolated cDNAs encoding PDE4A8 (phosphodiesterase 4 isoform A8), a new human cAMP-specific PDE4 isoform encoded by the PDE4A gene. PDE4A8 has a novel N-terminal region of 85 amino...
3.
Bolger G, Baillie G, Li X, Lynch M, Herzyk P, Mohamed A, et al.
Biochem J . 2006 May; 398(1):23-36. PMID: 16689683
The cAMP-specific phosphodiesterase PDE4D5 can interact with the signalling scaffold proteins RACK (receptors for activated C-kinase) 1 and beta-arrestin. Two-hybrid and co-immunoprecipitation analyses showed that RACK1 and beta-arrestin interact with...