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Lisa Bastarache

Explore the profile of Lisa Bastarache including associated specialties, affiliations and a list of published articles. Areas
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Articles 134
Citations 5027
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Recent Articles
1.
Ueland T, Younan S, Evans P, Sims J, Shroder M, Hawkins A, et al.
J Am Med Inform Assoc . 2025 Mar; PMID: 40085006
Objective: To validate a phenotyping algorithm for gradations of diverticular disease severity and investigate relationships between unmet social needs and disease severity. Materials And Methods: An algorithm was designed in...
2.
Roberts D, Bastarache L, He J, Lewis A, Aka I, Shotwell M, et al.
Pharmacogenet Genomics . 2025 Jan; 35(2):65-72. PMID: 39745345
Objectives: We aimed to classify genetic variants in RYR1 and CACNA1S associated with malignant hyperthermia using biobank genotyping data in patients exposed to triggering anesthetics without malignant hyperthermia phenotype. Methods:...
3.
Picou E, Davis H, Tang L, Bastarache L, Tharpe A
J Speech Lang Hear Res . 2024 Dec; 68(1):364-376. PMID: 39671254
Purpose: School-age children with unilateral hearing loss are at an increased risk of exhibiting academic difficulties. Yet, approximately half of children with unilateral hearing loss will not require additional support....
4.
Allaire P, Mayer J, Moat L, Gabor R, Shay J, He J, et al.
medRxiv . 2024 Dec; PMID: 39649603
Telomeres protect chromosomal integrity, and telomere length (TL) is influenced by environmental and genetic factors. While short-telomeres are linked to rare telomeropathies, this study explored the hypothesis that a "long-telomeropathy"...
5.
Douville N, Bastarache L, Bertucci-Richter E, Patil S, Jewell E, Freundlich R, et al.
PLoS One . 2024 Dec; 19(12):e0311318. PMID: 39636799
Background: Kidney dysfunction is a common complication in septic patients. Studies have identified numerous risk factors for sepsis-associated acute kidney injury (S-AKI), yet there is wide variability in the incidence...
6.
Park J, Levin M, Zhang D, Reza N, Mead J, Carruth E, et al.
JAMA Cardiol . 2024 Nov; 9(12):1124-1133. PMID: 39535783
Importance: The genetic factors that modulate the reduced penetrance and variable expressivity of heritable dilated cardiomyopathy (DCM) are largely unknown. BAG3 genetic variants have been implicated in both DCM and...
7.
Stead W, Lewis A, Giuse N, Williams A, Biaggioni I, Bastarache L
J Biomed Inform . 2024 Nov; 159():104743. PMID: 39486471
Objective: 2017 blood pressure (BP) categories focus on cardiac risk. We hypothesize that studying the balance between mechanisms that increase or decrease BP across the medical phenome will lead to...
8.
Douville N, Bastarache L, He J, Wu K, Vanderwerff B, Bertucci-Richter E, et al.
Anesthesiology . 2024 Sep; 142(1):52-71. PMID: 39250560
Background: Postoperative nausea and vomiting (PONV) is a key driver of unplanned admission and patient satisfaction after surgery. Because traditional risk factors do not completely explain variability in risk, this...
9.
Badrieh S, Bastarache L, Niu X, He J, Robinson J
AMIA Jt Summits Transl Sci Proc . 2024 Jun; 2024:498. PMID: 38827080
This study addresses rising incidence of pediatric venous thromboembolism by validating a VTE phenotype and developing a polygenic risk score (PRS) using UK Biobank data. Our findings demonstrate predictive value...
10.
Ike J, Smith I, Mosley D, Madden C, Grossarth S, Halle B, et al.
Arch Dermatol Res . 2024 May; 316(6):303. PMID: 38819581
Voriconazole exposure is associated with skin cancer, but it is unknown how the full spectrum of its metabolizer phenotypes impacts this association. We conducted a retrospective cohort study to determine...