Linus J Ostberg
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Explore the profile of Linus J Ostberg including associated specialties, affiliations and a list of published articles.
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11
Citations
45
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Recent Articles
1.
Ostberg L, Hoog J, Persson B
Chem Biol Interact
. 2024 Jan;
390:110876.
PMID: 38266864
The medium-chain dehydrogenase/reductase (MDR) superfamily has more than 600,000 members in UniProt as of March 2023. As the family has been growing, the proportion of functionally characterized proteins has been...
2.
Karlsson L, de Paula Michelatto D, Lusa A, DAlmeida Mgnani Silva C, Ostberg L, Persson B, et al.
Clin Biochem
. 2019 Jul;
73:50-56.
PMID: 31344365
Objective: Congenital adrenal hyperplasia (CAH) is an inborn error of metabolism and a common disorder of sex development where >90% of all cases are due to 21-hydroxylase deficiency. Novel and...
3.
Ostberg L, Persson B, Hoog J
BMC Biochem
. 2016 Jul;
17(1):16.
PMID: 27455956
Background: All known attempts to isolate and characterize mammalian class V alcohol dehydrogenase (class V ADH), a member of the large ADH protein family, at the protein level have failed....
4.
Ostberg L, Persson B, Hoog J
Chem Biol Interact
. 2014 Dec;
234:80-4.
PMID: 25479062
Mammalian alcohol dehydrogenase (ADH) is a protein family divided into six classes and the number of known family members is increasing rapidly. Several primate genomes are completely analyzed for the...
5.
Jornvall H, Landreh M, Ostberg L
Chem Biol Interact
. 2014 Dec;
234:75-9.
PMID: 25451589
It is now about half a century since molecular research on alcohol dehydrogenase (ADH), short-chain dehydrogenase/reductase (SDR) and medium-chain dehydrogenase/reductase (MDR) started. During this time, at least four stages of...
6.
Landreh M, Ostberg L, Pettersson T, Jornvall H
Biomol Concepts
. 2014 Nov;
5(3):257-64.
PMID: 25372757
Aggregation of transthyretin (TTR), a plasma-binding protein for thyroxine and retinol-binding protein, is the cause of several amyloid diseases. Disease-associated mutations are well known, but wild-type TTR is, to a...
7.
Landreh M, Ostberg L, Jornvall H
Biochem Biophys Res Commun
. 2014 Jul;
450(4):1433-8.
PMID: 25017908
The C-peptide of proinsulin exhibits multiple activities and several of the underlying molecular interactions are known. We recently showed that human C-peptide is sub-divided into a tripartite architecture and that...
8.
Barbaro M, Soardi F, Ostberg L, Persson B, de Mello M, Wedell A, et al.
Clin Endocrinol (Oxf)
. 2014 Jun;
82(1):37-44.
PMID: 24953648
Background: A detailed genotype-phenotype evaluation is presented by studying the enzyme activities of five rare amino acid substitutions (Arg233Gly, Ala265Ser, Arg341Trp, Arg366Cys and Met473Ile) identified in the CYP21A2 gene in...
9.
Ostberg L, Stromberg P, Hedberg J, Persson B, Hoog J
Chem Biol Interact
. 2012 Nov;
202(1-3):97-103.
PMID: 23159888
Alcohol dehydrogenase 5 (ADH5) is a member of the mammalian alcohol dehydrogenase family of yet undefined functions. ADH5 was first identified at the DNA level in human and deer mouse....
10.
Hoog J, Ostberg L
Chem Biol Interact
. 2011 Feb;
191(1-3):2-7.
PMID: 21291872
Mammalian alcohol dehydrogenase (ADH) can be divided into six classes, ADH1-ADH6, according to primary structure and function, where the classes are further subdivided into isozymes and allelic forms. With the...