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Linlin Sai

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Articles 25
Citations 142
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Recent Articles
1.
Zhang W, Qi X, Han M, Jia Q, Li X, Yin W, et al.
Ecotoxicol Environ Saf . 2025 Feb; 292:117969. PMID: 40020386
Silicosis is a prevalent occupational disease marked by progressive pulmonary fibrosis. Despite its significant health burden, the pathogenesis of silicosis remains unclear, and no specific therapeutic drugs are available. In...
2.
Zhang X, Sai L, Zhang W, Kan X, Jia Q, Bo C, et al.
Genes Environ . 2023 Sep; 45(1):23. PMID: 37658417
Background: Evidence showed that N-methyladenosine (mA) is strongly associated with male germline development. However, the role of mA methylation on circRNAs in amphibians remains unknown. In this study, we conducted...
3.
Zhang W, Jia Q, Han M, Zhang X, Guo L, Sun S, et al.
Folia Microbiol (Praha) . 2023 Aug; 69(1):1-15. PMID: 37644256
Bifidobacteria as a strictly anaerobic gram-positive bacteria, is widely distributed in the intestine, vagina and oral cavity, and is one of the first gut flora to colonize the early stages...
4.
Yang X, Li C, Yu G, Sun L, Guo S, Sai L, et al.
Chem Biol Interact . 2022 Feb; 355:109845. PMID: 35123993
Although it has been well recognized that benzene exposure can cause hematopoietic disorders such as aplastic anemia and leukemia, the underlying molecular mechanism remains to be fully understood. Emerging evidence...
5.
Bo C, Zhang J, Sai L, Du Z, Yu G, Li C, et al.
BMC Pulm Med . 2022 Jan; 22(1):13. PMID: 34991559
Background: Silicosis is a systemic disease characterized by persistent inflammation and incurable pulmonary fibrosis. Although great effort has been made to understand the pathogenesis of the disease, molecular mechanism underlying...
6.
Qi X, Geng X, Zhang J, Qu B, Zhang X, Jia Q, et al.
Genes Environ . 2021 Nov; 43(1):49. PMID: 34742356
Background: Increasing evidence suggested N-methyladenosine (mA) modification is crucial for male germline development. However, mA modification of lncRNAs gains a little attention in amphibians in recent years. Xenopus laevis (X....
7.
Jiao B, Guo S, Yang X, Sun L, Sai L, Yu G, et al.
Int Immunopharmacol . 2021 Jun; 98:107859. PMID: 34153664
To explore the potential role of HMGB1 on TDI-induced NLRP3 inflammasome activation, HBE cells were treated with TDI-HSA conjugate to observe the changes of HMGB1, TLR4, NF-κB, Nrf2 and NLRP3...
8.
Sai L, Qi X, Yu G, Zhang J, Zheng Y, Jia Q, et al.
Genes Environ . 2021 Jun; 43(1):23. PMID: 34130760
Background: Exposure to respirable crystalline silica (RCS) can induce accelerated silicosis (AS), a form of silicosis that is more progressive and severe form of silicosis. In this project we aimed...
9.
Zhang Y, Jia Q, Hu C, Han M, Guo Q, Li S, et al.
Toxicol Res (Camb) . 2021 Feb; 10(1):141-149. PMID: 33613981
Chlorpyrifos (CPF) is an organophosphate insecticide commonly used to treat fruit and vegetable crops. CPF can cause severe adverse effects on body organs including the liver and central nervous system....
10.
Jiao B, Chen Y, Yang Y, Sai L, Yu G, Bo C, et al.
Toxicol In Vitro . 2020 Oct; 70:105040. PMID: 33127434
Toluene-diisocyanate (TDI) is one of the main causes of occupational asthma. To study the role of autophagy in TDI-induced airway inflammation and airway remodeling in bronchial airway epithelial (16HBE) cells....