Ling Ling Few
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Explore the profile of Ling Ling Few including associated specialties, affiliations and a list of published articles.
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16
Citations
81
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Recent Articles
1.
Chang C, See Too W, Lim B, Few L
Acta Parasitol
. 2024 Jan;
69(1):426-438.
PMID: 38172465
Purpose: Entamoeba histolytica is one of the death-causing parasites in the world. Study on its lipid composition revealed that it is predominated by phosphatidylcholine and phosphatidylethanolamine. Further study revealed that...
2.
Muniandy S, Few L, Khoo B, Hassan S, Yvonne-Tee G, See Too W
Biomed Rep
. 2023 Oct;
19(6):91.
PMID: 37901877
MicroRNA (miR)-367 has a wide range of functions in gene regulation and as such plays a critical role in cell proliferation, differentiation and development, making it an essential molecule in...
3.
Chang C, Few L, Lim B, Yvonne-Tee G, Chew A, See Too W
Parasitol Res
. 2023 May;
122(7):1651-1661.
PMID: 37202563
The de novo biosynthesis of phosphatidylcholine and phosphatidylethanolamine in Entamoeba histolytica is largely dependent on the CDP-choline and CDP-ethanolamine pathways. Although the first enzymes of these pathways, EhCK1 and EhCK2,...
4.
Khalifa M, Few L, See Too W
Mini Rev Med Chem
. 2021 Dec;
22(9):1281-1288.
PMID: 34961459
Background: Pseudomonas aeruginosa is one of the most prevalent opportunistic pathogens in humans that has thrived and proved to be difficult to control in this "post-antibiotic era." Antibiotic alternatives are...
5.
Mohamed Sadom S, Raikundalia S, Shamsuddin S, See Too W, Few L
Genes (Basel)
. 2021 Jul;
12(6).
PMID: 34205960
Choline kinase (CK) is the enzyme catalyzing the first reaction in CDP-choline pathway for the biosynthesis of phosphatidylcholine. Higher expression of the α isozyme of CK has been implicated in...
6.
Raikundalia S, Mohamed Sadom S, Few L, See Too W
Oncol Lett
. 2021 Feb;
21(3):183.
PMID: 33574922
Choline kinase (ChK) catalyzes the first step in the CDP-choline pathway for the synthesis of phosphatidylcholine. The α isoform of this enzyme is overexpressed in various types of cancer and...
7.
Khalifa M, Few L, See Too W
Biomed Res Int
. 2020 Jul;
2020:1823485.
PMID: 32695809
Novel antimicrobial agents are crucial to combat antibiotic resistance in pathogenic bacteria. Choline kinase (ChoK) in bacteria catalyzes the synthesis of phosphorylcholine, which is subsequently incorporated into the cell wall...
8.
Ayub Khan S, Few L, See Too W
Mol Med Rep
. 2018 Mar;
17(5):7442-7450.
PMID: 29568919
Choline kinase (CK) is the first enzyme in the CDP-choline pathway for the synthesis of phosphatidylcholine, the most abundant phospholipid in the mammalian cell membrane. This enzyme exists as three...
9.
Chang C, Few L, Konrad M, See Too W
PLoS One
. 2016 May;
11(5):e0154702.
PMID: 27149373
Choline kinase beta (CKβ) is one of the CK isozymes involved in the biosynthesis of phosphatidylcholine. CKβ is important for normal mitochondrial function and muscle development as the lack of...
10.
Kuan C, See Too W, Few L
PLoS One
. 2016 Jan;
11(1):e0147886.
PMID: 26807725
Background: Ethanolamine kinase (EK) catalyzes the phosphorylation of ethanolamine, the first step in the CDP-ethanolamine pathway for the biosynthesis of phosphatidylethanolamine (PE). Human EK exists as EK1, EK2α and EK2β...