Ling-Zhi Ma
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Explore the profile of Ling-Zhi Ma including associated specialties, affiliations and a list of published articles.
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29
Citations
187
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Recent Articles
1.
Gan Y, Ma L, Zhang Y, You J, Guo Y, He Y, et al.
Nat Aging
. 2025 Feb;
PMID: 39979637
The early pathophysiology of Parkinson's disease (PD) is poorly understood. We analyzed 2,920 Olink-measured plasma proteins in 51,804 UK Biobank participants, identifying 859 incident PD cases after 14.45 years. We...
2.
Wu K, Xu Q, Liu Y, Feng Y, Han S, Zhang Y, et al.
Science
. 2025 Feb;
387(6736):892-900.
PMID: 39977508
Neuronal accumulation and spread of pathological α-synuclein (α-syn) fibrils are key events in Parkinson's disease (PD) pathophysiology. However, the neuronal mechanisms underlying the uptake of α-syn fibrils remain unclear. In...
3.
Sheng Z, Liu J, Ma J, Mi Y, Wang H, Guo F, et al.
J Alzheimers Dis
. 2025 Feb;
103(4):1023-1035.
PMID: 39956938
Background: Frailty, which is considered a potential modifiable risk factor for dementia, continues to generate debate when it comes to Alzheimer's disease (AD). Furthermore, the underlying pathological mechanisms linking frailty...
4.
Tang L, Ma L, Cheng-Kun S, Guo R, Tan L, Tan M
Curr Alzheimer Res
. 2024 Nov;
21(6):411-422.
PMID: 39572920
Background: This study investigated the relationship between Life's Essential 8 (LE8), a recently updated lifestyle-related health factor, and cognition across multiple life stages. Methods: We enrolled 1098 cognitively normal participants...
5.
Ma L, Ge Y, Zhang Y, Cui X, Feng J, Cheng W, et al.
Geroscience
. 2024 Oct;
PMID: 39441508
A thorough understanding and identification of potential determinants leading to frailty are imperative for the development of targeted interventions aimed at its prevention or mitigation. We investigated the potential determinants...
6.
Huang L, Fu Y, Zhang Y, Hu H, Ma L, Ge Y, et al.
CNS Neurosci Ther
. 2024 Oct;
30(10):e70057.
PMID: 39404063
Aims: Brain structural alterations begin long before the presentation of brain disorders; therefore, we aimed to systematically investigate a wide range of influencing factors on neuroimaging markers of brain health....
7.
Han B, Ma L, Han S, Mi Y, Liu J, Sheng Z, et al.
J Alzheimers Dis
. 2024 Aug;
100(4):1333-1343.
PMID: 39093070
Background: The relationship between Alzheimer's disease (AD)-related pathology and cognition was not exactly consistent. Objective: To explore whether the association between AD pathology and cognition can be moderated by frailty....
8.
Ge Y, Chen S, Wu B, Zhang Y, Wang J, He X, et al.
Alzheimers Dement
. 2024 Jul;
20(9):6243-6256.
PMID: 39023044
Introduction: Alzheimer's disease (AD) is a devastating neurological disease with complex genetic etiology. Yet most known loci have only identified from the late-onset type AD in populations of European ancestry....
9.
Huang L, Ge Y, Fu Y, Zhao Y, Ou Y, Zhang Y, et al.
Geroscience
. 2024 Jun;
46(6):6257-6268.
PMID: 38822946
Considerable uncertainty remains regarding the associations of multiple factors with brain health. We aimed to conduct an exposome-wide association study on neurodegenerative disease and neuropsychiatry disorders using data of participants...
10.
Gao P, Ma L, Wang X, Wu B, Huang Y, Wang Z, et al.
Transl Psychiatry
. 2024 May;
14(1):212.
PMID: 38802408
Physical frailty and genetic factors are both risk factors for increased dementia; nevertheless, the joint effect remains unclear. This study aimed to investigated the long-term relationship between physical frailty, genetic...