Line Labbe
Overview
Explore the profile of Line Labbe including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
261
Followers
0
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Related Specialties
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Recent Articles
1.
Kassir N, Labbe L, Delaloye J, Mouksassi M, Lapeyraque A, Alvarez F, et al.
Br J Clin Pharmacol
. 2014 Jul;
77(6):1051-63.
PMID: 24977292
Aims: The objectives of this study were to develop a population pharmacokinetic (PopPK) model for tacrolimus in paediatric liver transplant patients and determine optimal sampling strategies to estimate tacrolimus exposure...
2.
Seng Yue C, Gallicano K, Labbe L, Ducharme M
J Pharm Pharm Sci
. 2013 Sep;
16(3):424-40.
PMID: 24021291
Purpose: Iron-containing products are atypical in terms of their pharmacokinetic properties because iron is only removed by plasma sampling and is non-linear. This study aims to present a novel way...
3.
Delaloye J, Kassir N, Lapeyraque A, Alvarez F, Lallier M, Beaunoyer M, et al.
Ther Drug Monit
. 2011 Jul;
33(4):380-6.
PMID: 21743386
Objective: To develop and validate limited sampling strategies (LSSs) for tacrolimus in pediatric liver transplant recipients. Methods: Thirty-six 12-hour pharmacokinetic profiles from 28 pediatric liver transplant recipients (0.4-18.5 years) were...
4.
Hamelin B, Zakrzewski-Jakubiak M, Robitaille N, Bogaty P, Labbe L, Turgeon J
J Clin Pharmacol
. 2010 Dec;
51(9):1286-92.
PMID: 21148050
The angiotensin-converting enzyme (ACE) gene is a candidate genetic locus for coronary artery disease (CAD). Studies investigating the relationship between the ACE-insertion/deletion (I/D) gene polymorphism and myocardial infarction (MI) have...
5.
Pettersen G, Mouksassi M, Theoret Y, Labbe L, Faure C, Nguyen B, et al.
Br J Clin Pharmacol
. 2009 Jan;
67(2):216-27.
PMID: 19173681
What Is Already Known About This Subject: The use of intravenous pantoprazole, a proton pump inhibitor, has been increasing in the paediatric intensive care unit. Despite this increased use, data...
6.
Michaud V, Mouksassi M, Labbe L, Belanger P, Ferron L, Gilbert M, et al.
Ther Drug Monit
. 2006 Dec;
28(6):779-83.
PMID: 17164694
CYP1A2 is involved in the metabolism of both caffeine and propafenone, a class Ic antiarrhythmic agent. Despite the widespread consumption of caffeine, drug-drug interactions with this agent are often overlooked....
7.
Motsinger A, Ritchie M, Shafer R, Robbins G, Morse G, Labbe L, et al.
Pharmacogenet Genomics
. 2006 Oct;
16(11):837-45.
PMID: 17047492
Objective: For the HIV-1 reverse transcriptase inhibitor efavirenz, variant drug transporter gene ABCB1 may predict virologic response but not plasma efavirenz exposure. Conversely, variant drug metabolizing enzyme gene CYP2B6 predicts...
8.
Labbe L, Verotta D
J Pharmacokinet Pharmacodyn
. 2006 Jun;
33(4):519-42.
PMID: 16786410
Long term therapy with antiretroviral agents in HIV-infected patients often result in failure to suppress the virus load. Imperfect adherence to prescribed antiviral drugs is an important factor explaining the...
9.
Kenna L, Labbe L, Barrett J, Pfister M
AAPS J
. 2005 Dec;
7(2):E390-407.
PMID: 16353919
Partial adherence with a prescribed or randomly assigned dose gives rise to unintended variability in actual drug exposure in clinical practice and during clinical trials. There are tremendous costs associated...
10.
Haas D, Smeaton L, Shafer R, Robbins G, Morse G, Labbe L, et al.
J Infect Dis
. 2005 Nov;
192(11):1931-42.
PMID: 16267764
Background: Efavirenz and nelfinavir are metabolized by cytochrome P-450 (CYP) 2B6 and CYP2C19, respectively, with some involvement by CYP3A. Nelfinavir is a substrate for P-glycoprotein, which is encoded by MDR1....