Lindsay McCaw
Overview
Explore the profile of Lindsay McCaw including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
128
Followers
0
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Recent Articles
1.
Spaner D, McCaw L, Wang G, Tsui H, Shi Y
Cancer Med
. 2019 Mar;
8(4):1540-1550.
PMID: 30843659
Methods to deepen clinical responses to ibrutinib are needed to improve outcomes for patients with chronic lymphocytic leukemia (CLL). This study aimed to determine the safety and efficacy of combining...
2.
Shi Y, Wang G, Muhowski E, McCaw L, Wang C, Bjarnason G, et al.
Leukemia
. 2019 Jan;
33(7):1650-1662.
PMID: 30696950
Glucocorticoid (GC) receptor (GR) phosphorylation and signature genes were studied in chronic lymphocytic leukemia (CLL) cells to help place GCs within modern treatment algorithms. In contrast to normal B and...
3.
Zhu F, McCaw L, Spaner D, Gorczynski R
Leuk Res
. 2018 Jan;
66:28-38.
PMID: 29353760
The tumor microenvironment (TME) is critical to the longevity of tumor B cells in chronic lymphocytic leukemia (CLL). Bone marrow mesenchymal stem cells (BMMSCs) and the cytokines they produce including...
4.
McCaw L, Shi Y, Wang G, Li Y, Spaner D
EBioMedicine
. 2016 Dec;
15:24-35.
PMID: 27932296
Recent studies suggest there is a high incidence of elevated low-density lipoprotein (LDL) levels in Chronic Lymphocytic Leukemia (CLL) patients and a survival benefit from cholesterol-lowering statin drugs. The mechanisms...
5.
Oppermann S, Lam A, Tung S, Shi Y, McCaw L, Wang G, et al.
Oncotarget
. 2016 Sep;
7(45):72608-72621.
PMID: 27579615
Glucorticoids (GCs) such as dexamethasone (DEX) remain important treatments for Chronic Lymphocytic Leukemia (CLL) but the mechanisms are poorly understood and resistance is inevitable. Proliferation centers (PC) in lymph nodes...
6.
Spaner D, Wang G, McCaw L, Li Y, Disperati P, Cussen M, et al.
Haematologica
. 2016 Jan;
101(5):e192-5.
PMID: 26819050
No abstract available.
7.
Li Y, Shi Y, McCaw L, Li Y, Zhu F, Gorczynski R, et al.
Blood
. 2015 Jun;
126(6):766-78.
PMID: 26041742
The regulation of toll-like receptor (TLR) signaling in a tumor microenvironment is poorly understood despite its importance in cancer biology. To address this problem, TLR7-responses of chronic lymphocytic leukemia (CLL)...
8.
Tomic J, McCaw L, Li Y, Hough M, Ben-David Y, Moffat J, et al.
Exp Hematol
. 2013 Apr;
41(8):675-86.
PMID: 23597602
CLL cells are characterized by high levels of proteins that are post-translationally modified by O-linked β-N-acetylglucosamine (O-GlcNAc) moieties, but it is not clear whether O-GlcNAc is a relevant therapeutic target....