Linda Howard
Overview
Explore the profile of Linda Howard including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
676
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Recent Articles
1.
Keighron C, Avazzadeh S, Goljanek-Whysall K, McDonagh B, Howard L, Ritter T, et al.
Biomedicines
. 2023 Mar;
11(3).
PMID: 36979707
Neurodegeneration is hallmarked by the progressive loss of dopaminergic neurons and/or a significant increase in protein aggregates in the brain. Neurodegenerative diseases are a leading cause of death worldwide with...
2.
Mohamed S, Duffy A, McInerney V, Krawczyk J, Hayat A, Naughton S, et al.
Cytotherapy
. 2022 Aug;
24(12):1259-1267.
PMID: 35999133
Background Aims: Approximately 1 in 3 patients with critical limb ischemia (CLI) are not suitable for surgical or endovascular revascularization. Those "no-option" patients are at high risk of amputation and...
3.
Ding Y, Carvalho E, Murphy C, McInerney V, Krawczyk J, OBrien T, et al.
Stem Cell Res
. 2022 Jun;
63:102850.
PMID: 35772298
No abstract available.
4.
Shortiss C, Howard L, McMahon S
Cells
. 2021 Aug;
10(8).
PMID: 34440872
Spinal cord injury (SCI) is a devastating trauma that can cause permanent disability, life-long chronic issues for sufferers and is a big socioeconomic burden. Regenerative medicine aims to overcome injury...
5.
Mohamed S, Viknaswaran N, Doran J, Sanz-Nogues C, Ahmed K, Howard L, et al.
Ann Vasc Surg
. 2021 Apr;
75:171-178.
PMID: 33819592
Background: The ERICVA score was derived to predict amputation-free survival in patients with critical limb ischemia (CLI). It may be a useful tool to stratify patients in trials of novel...
6.
Ding Y, OBrien A, De La Cruz B, Yang M, Lu Y, Qian X, et al.
Stem Cell Res
. 2021 Feb;
53:102254.
PMID: 33631419
NRXN1 deletions are commonly found in autism spectrum disorder (ASD) and other neurodevelopmental/neuropsychiatric disorders. Derivation of induced pluripotent stem cells (iPSCs) from different diseases involving different deletion regions are essential,...
7.
Ding Y, OBrien A, De La Cruz B, Yang M, FitzGerald J, Yang G, et al.
Stem Cell Res
. 2021 Feb;
52:102222.
PMID: 33578364
NRXN1 encodes thousands of splicing variants categorized into long NRXN1α, short NRXN1β and extremely short NRXN1γ, which exert differential roles in neuronal excitation/inhibition. NRXN1α deletions are common in autism spectrum...
8.
Ding Y, De La Cruz B, McInerney V, Lu Y, Yang G, Qian X, et al.
Stem Cell Res
. 2020 Dec;
49:102101.
PMID: 33370872
The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three...
9.
Mohamed S, Howard L, McInerney V, Hayat A, Krawczyk J, Naughton S, et al.
Cytotherapy
. 2020 Apr;
22(6):313-321.
PMID: 32273232
Background: Critical limb ischemia (CLI) is the most severe manifestation of peripheral vascular disease. Revascularization is the preferred therapy, but it is not achievable in 25%-40% of patients due to...
10.
Patar A, Dockery P, McMahon S, Howard L
Biology (Basel)
. 2020 Mar;
9(3).
PMID: 32183469
The failure of the spinal cord to regenerate can be attributed both to a lack of trophic support for regenerating axons and to upregulation of inhibitory factors such as chondroitin...