Linda Hofmann
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Explore the profile of Linda Hofmann including associated specialties, affiliations and a list of published articles.
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18
Citations
142
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Recent Articles
1.
Wang Y, Hofmann L, Huber D, Lochbaum R, Ludwig S, Brunner C, et al.
J Clin Med
. 2024 Sep;
13(18).
PMID: 39336917
: Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic disorder leading to frequent bleeding in several organs. As HHT diagnosis is demanding and depends on clinical criteria, liquid biopsy would be...
2.
Theodoraki M, Huber D, Hofmann L, Werner L, Idel C, Fleckner J, et al.
BMC Cancer
. 2024 Sep;
24(1):1173.
PMID: 39304856
Background: Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles they...
3.
Kors T, Meier M, Muhlenbruch L, Betzler A, Oliveri F, Bens M, et al.
Front Immunol
. 2024 Aug;
15:1408173.
PMID: 39136024
Introduction: The human leukocyte antigen complex (HLA) is essential for inducing specific immune responses to cancer by presenting tumor-associated peptides (TAP) to T cells. Overexpressed tumor associated antigens, mainly cancer-testis...
4.
Idel C, Fleckner J, Plotze-Martin K, Werner L, Rades D, Theodoraki M, et al.
BMC Cancer
. 2024 Apr;
24(1):459.
PMID: 38609887
Background: Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and...
5.
Kors T, Hofmann L, Betzler A, Payer K, Bens M, Truong J, et al.
Cancer Res Commun
. 2024 Feb;
4(2):571-587.
PMID: 38329386
Significance: Patients with HPV-negative OPSCC have a poorer prognosis due to distinct molecular pathways. This study reveals significant transcriptomic differences between HPV-negative and HPV-positive OPSCC, identifying INHBA as a key...
6.
Hofmann L, Harasymczuk M, Huber D, Szczepanski M, Dworacki G, Whiteside T, et al.
Cancers (Basel)
. 2023 Nov;
15(22).
PMID: 38001706
Immunoregulatory Arginase-1 (Arg-1) is present in the tumor microenvironment of solid tumors. Its association to clinicopathology and its prognostic impact are inconsistent among different tumor types and biological fluids. This...
7.
Theodoraki M, Hofmann L, Huber D, Brunner C, Hoffmann T, Idel C, et al.
Oncol Lett
. 2023 Apr;
25(5):200.
PMID: 37113401
Exosomes play an important role in the individual immune regulation in patients with head and neck squamous cell carcinoma (HNSCC) as part of the tumor microenvironment. Patients with HNSCC with...
8.
Hofmann L, Waizenegger M, Roth R, Schmitteckert S, Engelhardt D, Schuler P, et al.
Front Oncol
. 2023 Jan;
12:1043199.
PMID: 36686733
Background: Epithelial to mesenchymal transition (EMT) is a key process in carcinogenesis of head and neck squamous cell carcinoma (HNSCC), contributing to tumor invasiveness, distant metastasis, and recurrence. Exosomes are...
9.
Li X, Ospitalieri S, Robberechts T, Hofmann L, Schmid C, Rijal Upadhaya A, et al.
Brain
. 2022 Oct;
145(10):3558-3570.
PMID: 36270003
Alzheimer's disease is neuropathologically characterized by the deposition of the amyloid β-peptide (Aβ) as amyloid plaques. Aβ plaque pathology starts in the neocortex before it propagates into further brain regions....
10.
Hofmann L, Kors T, Ezic J, Niesler B, Roth R, Ludwig S, et al.
Front Cell Dev Biol
. 2022 Sep;
10:971596.
PMID: 36072342
Head and neck squamous cell carcinomas (HNSCC) lack tumor-specific biomarkers. Exosomes from HNSCC patients carry immunomodulatory molecules, and correlate with clinical parameters. We compared miRNA profiles of plasma- and saliva-derived...