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Linda C H Yu

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Articles 11
Citations 266
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Recent Articles
1.
Chen Y, Shin J, Wei H, Lin C, Yu L, Liao W, et al.
Food Funct . 2021 Jan; 12(4):1639-1650. PMID: 33481975
The fungal immunomodulatory protein Ling Zhi-8 (LZ-8) isolated from Ganoderma lucidum (GL) regulates immune cells and inhibits tumor growth; however, the role of LZ-8 in protecting intestinal epithelial cells (IECs)...
2.
Wei S, Yang-Yen H, Tsao P, Weng M, Tung C, Yu L, et al.
Inflamm Bowel Dis . 2017 Sep; 23(10):1730-1740. PMID: 28906292
Background: The integrity of the gut barrier in patients with inflammatory bowel disease is known to be impaired but the exact mechanisms remain mostly unknown. SHANK3 mutations are associated with...
3.
Wu L, Peng W, Kuo W, Huang C, Ni Y, Lu K, et al.
Am J Pathol . 2014 Jun; 184(8):2260-74. PMID: 24911373
Abnormal bacterial adherence and internalization in enterocytes have been documented in Crohn disease, celiac disease, surgical stress, and intestinal obstruction and are associated with low-level interferon (IFN)-γ production. How commensals...
4.
Lee T, Wang H, Chiu H, Lien W, Chen M, Yu L, et al.
J Clin Gastroenterol . 2010 Mar; 44(5):e96-100. PMID: 20216431
Objective: Ischemic colitis (IC) spans a broad spectrum from self-limiting illness to intestinal gangrene and mortality. Prognostic factors specifically for nonpostoperative IC were not fully characterized. We aim to focus...
5.
Yu L, Huang C, Kuo W, Sayer H, Turner J, Buret A
Int J Parasitol . 2008 Feb; 38(8-9):923-34. PMID: 18281046
Infection with Giardia duodenalis is one of the most common causes of waterborne diarrheal disease worldwide. Mechanisms of pathogenesis and host response in giardiasis remain incompletely understood. Previous studies have...
6.
Yu L, Turner J, Buret A
Exp Cell Res . 2006 Jul; 312(17):3276-86. PMID: 16860318
Recent findings indicate that enhanced glucose uptake protects enterocytes from excessive apoptosis and barrier defects induced by LPS exposure. The aim of this study was to characterize the mechanisms responsible...
7.
Yu L, Flynn A, Turner J, Buret A
FASEB J . 2005 Nov; 19(13):1822-35. PMID: 16260652
Excessive apoptosis induced by enteric microbes leads to epithelial barrier defects. This mechanism has been implicated in the pathogenesis of inflammatory bowel diseases (IBD) and bacterial enteritis. The sodium-dependent glucose...
8.
Montagnac G, Molla-Herman A, Bouchet J, Yu L, Conrad D, Perdue M, et al.
J Immunol . 2005 Apr; 174(9):5562-72. PMID: 15843555
In mouse models of food allergy, we recently characterized a new CD23b-derived splice form lacking extracellular exon 5, bDelta5, which undergoes constitutive internalization and mediates the transepithelial transport of free...
9.
Montagnac G, Yu L, Bevilacqua C, Heyman M, Conrad D, Perdue M, et al.
Traffic . 2005 Feb; 6(3):230-42. PMID: 15702991
The low affinity receptor for IgE (CD23) was recently implicated in the trans-epithelial transport of IgE-allergen complexes from the luminal side of enterocytes in animal models for intestinal allergy. Here,...
10.
Scott K, Yu L, Buret A
Infect Immun . 2004 May; 72(6):3536-42. PMID: 15155662
T-cell-mediated pathogenesis has been documented in various idiopathic and microbially induced intestinal disorders. Diffuse microvillous shortening seen in giardiasis is responsible for disaccharidase insufficiencies and malabsorption of electrolytes, nutrients, and...