Linas Mazutis
Overview
Explore the profile of Linas Mazutis including associated specialties, affiliations and a list of published articles.
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Articles
57
Citations
6776
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Recent Articles
1.
Juzenas S, Goda K, Kiseliovas V, Zvirblyte J, Quintinal-Villalonga A, Siurkus J, et al.
Nucleic Acids Res
. 2025 Jan;
53(2).
PMID: 39797728
The expansion of single-cell analytical techniques has empowered the exploration of diverse biological questions at the individual cells. Droplet-based single-cell RNA sequencing (scRNA-seq) methods have been particularly widely used due...
2.
Moorman A, Benitez E, Cambuli F, Jiang Q, Mahmoud A, Lumish M, et al.
Nature
. 2025 Jan;
637(8047):E28.
PMID: 39789339
No abstract available.
3.
Takashima S, Sharma R, Chang W, Calafiore M, Fu Y, Jansen S, et al.
Nat Commun
. 2025 Jan;
16(1):138.
PMID: 39746933
The role of the immune system in regulating tissue stem cells remains poorly understood, as does the relationship between immune-mediated tissue damage and regeneration. Graft vs. host disease (GVHD) occurring...
4.
Moorman A, Moorman A, Benitez E, Benitez E, Cambuli F, Cambulli F, et al.
Nature
. 2024 Oct;
637(8047):947-954.
PMID: 39478232
As cancers progress, they become increasingly aggressive-metastatic tumours are less responsive to first-line therapies than primary tumours, they acquire resistance to successive therapies and eventually cause death. Mutations are largely...
5.
Kousa A, Jahn L, Zhao K, Flores A, Acenas 2nd D, Lederer E, et al.
Nat Immunol
. 2024 Aug;
25(9):1593-1606.
PMID: 39112630
The thymus is essential for establishing adaptive immunity yet undergoes age-related involution that leads to compromised immune responsiveness. The thymus is also extremely sensitive to acute insult and although capable...
6.
Zaidi S, Park J, Chan J, Roudier M, Zhao J, Gopalan A, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(28):e2322203121.
PMID: 38968122
Targeting cell surface molecules using radioligand and antibody-based therapies has yielded considerable success across cancers. However, it remains unclear how the expression of putative lineage markers, particularly cell surface molecules,...
7.
Zvirblyte J, Nainys J, Juzenas S, Goda K, Kubiliute R, Dasevicius D, et al.
Commun Biol
. 2024 Jun;
7(1):780.
PMID: 38942917
Clear cell renal cell carcinoma (ccRCC) is the most prevalent form of renal cancer, accounting for over 75% of cases. The asymptomatic nature of the disease contributes to late-stage diagnoses...
8.
Pranauskaite E, Milkus V, Ritmejeris J, Zilionis R, Mazutis L
Anal Chem
. 2024 Apr;
96(18):6898-6905.
PMID: 38649796
High-throughput single-cell analysis typically relies on the isolation of cells of interest in separate compartments for subsequent phenotypic or genotypic characterization. Using microfluidics, this is achieved by isolating individual cells...
9.
Zaidi S, Park J, Chan J, Roudier M, Zhao J, Gopalan A, et al.
bioRxiv
. 2024 Apr;
PMID: 38645034
Targeting cell surface molecules using radioligand and antibody-based therapies has yielded considerable success across cancers. However, it remains unclear how the expression of putative lineage markers, particularly cell surface molecules,...
10.
Nazaret A, Fan J, Lavallee V, Burdziak C, Cornish A, Kiseliovas V, et al.
bioRxiv
. 2023 Nov;
PMID: 38014231
Biological insights often depend on comparing conditions such as disease and health, yet we lack effective computational tools for integrating single-cell genomics data across conditions or characterizing transitions from normal...