Lina Antounians
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Explore the profile of Lina Antounians including associated specialties, affiliations and a list of published articles.
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35
Citations
559
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Recent Articles
1.
Doktor F, Antounians L, Figueira R, Khalaj K, Duci M, Zani A
Stem Cells Transl Med
. 2025 Jan;
14(1.
PMID: 39823257
Disruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic hernia (CDH) and oligohydramnios. Both entities have high morbidity...
2.
Ben-Meir E, Antounians L, Eisha S, Ratjen F, Zani A, Grasemann H
ERJ Open Res
. 2024 Dec;
10(6).
PMID: 39655173
Background: The aim of this study was to quantify mediators of neutrophilic inflammation within airway extracellular vesicles (EVs) of children treated for a cystic fibrosis (CF) pulmonary exacerbation (PEx). Methods:...
3.
Doktor F, Figueira R, Fortuna V, Biouss G, Stasiewicz K, Obed M, et al.
J Control Release
. 2024 Nov;
377:427-441.
PMID: 39577465
Oligohydramnios (decreased amniotic fluid volume for gestational age) is a severe condition associated with high morbidity and mortality mainly due to fetal pulmonary hypoplasia. Currently, there are limited treatment options...
4.
Doktor F, Lo E, Fortuna V, Khalaj K, Garcia M, Figueira R, et al.
Pediatr Surg Int
. 2024 Oct;
40(1):278.
PMID: 39467854
Purpose: Amniotic fluid stem cell extracellular vesicles (AFSC-EVs) hold regenerative potential to treat hypoplastic lungs secondary to congenital diaphragmatic hernia (CDH). This study aims to investigate sex-specific differences in pulmonary...
5.
Antounians L, Figueira R, Kukreja B, Litvack M, Zani-Ruttenstock E, Khalaj K, et al.
Sci Adv
. 2024 Jul;
10(30):eadn5405.
PMID: 39058789
Antenatal administration of extracellular vesicles from amniotic fluid stem cells (AFSC-EVs) reverses features of pulmonary hypoplasia in models of congenital diaphragmatic hernia (CDH). However, it remains unknown which lung cellular...
6.
Biouss G, Antounians L, Aguet J, Kopcalic K, Fakhari N, Baranger J, et al.
Sci Rep
. 2024 Jun;
14(1):13680.
PMID: 38871804
Congenital diaphragmatic hernia (CDH) is a birth defect characterized by incomplete closure of the diaphragm, herniation of abdominal organs into the chest, and compression of the lungs and the heart....
7.
Gordillo-Sampedro S, Antounians L, Wei W, Mufteev M, Lendemeijer B, Kushner S, et al.
Mol Cell Neurosci
. 2024 Apr;
129:103933.
PMID: 38663691
Astrocytes are in constant communication with neurons during the establishment and maturation of functional networks in the developing brain. Astrocytes release extracellular vesicles (EVs) containing microRNA (miRNA) cargo that regulates...
8.
Figueira R, Khoshgoo N, Doktor F, Khalaj K, Islam T, Moheimani N, et al.
J Pediatr Surg
. 2024 Mar;
59(9):1771-1777.
PMID: 38519389
Background: The severity of pulmonary hypoplasia is a main determinant of outcome for babies with congenital diaphragmatic hernia (CDH). Antenatal administration of extracellular vesicles derived from amniotic fluid stem cells...
9.
Doktor F, Figueira R, Khalaj K, Ijaz A, Lacher M, Blundell M, et al.
Pediatr Surg Int
. 2023 Nov;
39(1):296.
PMID: 37981587
Purpose: Lineage tracing is key to study the fate of individual cells and their progeny especially in developmental biology. To conduct these studies, we aimed to establish a reproducible model...
10.
Blundell M, Doktor F, Figueira R, Khalaj K, Biouss G, Antounians L, et al.
Pediatr Surg Int
. 2023 Nov;
39(1):291.
PMID: 37955723
Purpose: Congenital diaphragmatic hernia (CDH) survivors may experience neurodevelopmental impairment, whose etiology remains elusive. Preclinical evidence indicates that amniotic fluid stem cell extracellular vesicle (AFSC-EV) administration promotes lung development but...