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Lina-Marcela Diaz-Gallo

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Recent Articles
1.
Lindelof L, Rantapaa-Dahlqvist S, Lundtoft C, Sandling J, Leonard D, Sayadi A, et al.
J Autoimmun . 2024 Jan; 143:103166. PMID: 38219652
The complement system plays a central role in the pathogenesis of Systemic Lupus Erythematosus (SLE), but most studies have focused on the classical pathway. Ficolin-3 is the main initiator of...
2.
Leclair V, Galindo-Feria A, Rothwell S, Krystufkova O, Zargar S, Mann H, et al.
EBioMedicine . 2023 Sep; 96:104804. PMID: 37769433
Background: In patients with idiopathic inflammatory myopathies (IIM), autoantibodies are associated with specific clinical phenotypes suggesting a pathogenic role of adaptive immunity. We explored if autoantibody profiles are associated with...
3.
Argyriou A, Horuluoglu B, Galindo-Feria A, Diaz-Boada J, Sijbranda M, Notarnicola A, et al.
EMBO Mol Med . 2023 Jul; 15(10):e17240. PMID: 37522383
Idiopathic inflammatory myopathies (IIM) are rare autoimmune systemic diseases characterized by muscle weakness and the presence of muscle-infiltrating T cells. IIM represent a clinical challenge due to heterogeneity of symptoms...
4.
Sysojev A, Saevarsdottir S, Diaz-Gallo L, Silberberg G, Alfredsson L, Klareskog L, et al.
Rheumatology (Oxford) . 2023 Jun; 63(5):1221-1229. PMID: 37326842
Objectives: To investigate the influence of genetic factors on persistence with treatment of early RA with MTX monotherapy. Methods: We conducted a genome-wide association study (GWAS) in a sample of...
5.
Qin C, Diaz-Gallo L, Tang B, Wang Y, Nguyen T, Harder A, et al.
Eur J Epidemiol . 2023 Apr; 38(7):809-819. PMID: 37052755
Despite increasing therapeutic options to treat rheumatoid arthritis (RA), many patients fail to reach treatment targets. The use of antidiabetic drugs like thiazolidinediones has been associated with lower RA risk....
6.
Hensvold A, Horuluoglu B, Sahlstrom P, Thyagarajan R, Diaz Boada J, Hansson M, et al.
J Autoimmun . 2023 Mar; 136:103022. PMID: 37001434
A majority of circulating IgG is produced by plasma cells residing in the bone marrow (BM). Long-lived BM plasma cells constitute our humoral immune memory and are essential for infection-specific...
7.
Elbagir S, Diaz-Gallo L, Grosso G, Zickert A, Gunnarsson I, Mahler M, et al.
Rheumatology (Oxford) . 2022 Jun; 62(2):924-933. PMID: 35642868
Objectives: Emerging evidence demonstrates that aPS-PT associate with thrombotic events. Genetic predisposition, including HLA-DRB1 alleles, is known to contribute to the occurrence of conventional aPL [anti-β2glycoprotein-I (anti-β2GPI) and aCL]. We...
8.
Diaz-Gallo L, Oke V, Lundstrom E, Elvin K, Wu Y, Eketjall S, et al.
ACR Open Rheumatol . 2021 Oct; 4(1):27-39. PMID: 34658170
Objective: The heterogeneity of systemic lupus erythematosus (SLE) constitutes clinical and therapeutical challenges. We therefore studied whether unrecognized disease subgroups can be identified by using autoantibody profiling together with HLA-DRB1...
9.
Diaz-Gallo L, Brynedal B, Westerlind H, Sandberg R, Ramskold D
PLoS One . 2021 Apr; 16(4):e0250282. PMID: 33901204
Understanding the genetic background of complex diseases requires the expansion of studies beyond univariate associations. Therefore, it is important to use interaction assessments of risk factors in order to discover...
10.
Diaz-Gallo L, Ramskold D, Shchetynsky K, Folkersen L, Chemin K, Brynedal B, et al.
Ann Rheum Dis . 2018 Jul; 77(10):1454-1462. PMID: 29967194
Objective: In anti-citrullinated protein antibody positive rheumatoid arthritis (ACPA-positive RA), a particular subset of alleles, called shared epitope (SE) alleles, is a highly influential genetic risk factor. Here, we investigated...