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Lily Q Wang

Explore the profile of Lily Q Wang including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bosc E, Anastasie J, Soualmia F, Coric P, Kim J, Wang L, et al.
Cell Death Dis . 2022 Nov; 13(11):959. PMID: 36379916
Caspase-2 (Casp2) is a promising therapeutic target in several human diseases, including nonalcoholic steatohepatitis (NASH) and Alzheimer's disease (AD). However, the design of an active-site-directed inhibitor selective to individual caspase...
2.
Kim J, Wang L, Sladky V, Oh T, Liu J, Trinh K, et al.
Cell Metab . 2022 Aug; 34(10):1548-1560.e6. PMID: 36041455
Sterol deficiency triggers SCAP-mediated SREBP activation, whereas hypernutrition together with ER stress activates SREBP1/2 via caspase-2. Whether these pathways interact and how they are selectively activated by different dietary cues...