Lihong Wang-Bishop
Overview
Explore the profile of Lihong Wang-Bishop including associated specialties, affiliations and a list of published articles.
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12
Citations
305
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Recent Articles
1.
Wang-Bishop L, Wehbe M, Pastora L, Yang J, Kimmel B, Garland K, et al.
ACS Nano
. 2024 Apr;
18(18):11631-11643.
PMID: 38652829
Pharmacological activation of the retinoic acid-inducible gene I (RIG-I) pathway holds promise for increasing tumor immunogenicity and improving the response to immune checkpoint inhibitors (ICIs). However, the potency and clinical...
2.
Wang-Bishop L, Kimmel B, Ngwa V, Madden M, Baljon J, Florian D, et al.
Sci Immunol
. 2023 May;
8(83):eadd1153.
PMID: 37146128
The tumor-associated vasculature imposes major structural and biochemical barriers to the infiltration of effector T cells and effective tumor control. Correlations between stimulator of interferon genes (STING) pathway activation and...
3.
Lu H, Gomaa A, Wang-Bishop L, Ballout F, Hu T, McDonald O, et al.
Cancers (Basel)
. 2022 Mar;
14(6).
PMID: 35326553
Unfolded protein response (UPR) protects malignant cells from endoplasmic reticulum stress-induced apoptosis. We report that Aurora kinase A (AURKA) promotes cancer cell survival by activating UPR in esophageal adenocarcinoma (EAC)....
4.
Carson C, Becker K, Garland K, Pagendarm H, Stone P, Arora K, et al.
J Control Release
. 2022 Mar;
345:354-370.
PMID: 35301055
Traditional approaches to cancer vaccines elicit weak CD8 T cell responses and have largely failed to meet clinical expectations. This is in part due to inefficient antigen cross-presentation, inappropriate selection...
5.
Garland K, Rosch J, Carson C, Wang-Bishop L, Hanna A, Sevimli S, et al.
Front Immunol
. 2021 Dec;
12:753472.
PMID: 34899704
When compartmentally mislocalized within cells, nucleic acids can be exceptionally immunostimulatory and can even trigger the immune-mediated elimination of cancer. Specifically, the accumulation of double-stranded DNA in the cytosol can...
6.
Wehbe M, Wang-Bishop L, Becker K, Shae D, Baljon J, He X, et al.
J Control Release
. 2020 Nov;
330:1118-1129.
PMID: 33189789
The stimulator of interferon genes (STING) pathway plays an important role in the immune surveillance of cancer and, accordingly, agonists of STING signaling have recently emerged as promising therapeutics for...
7.
Wang-Bishop L, Wehbe M, Shae D, James J, Hacker B, Garland K, et al.
J Immunother Cancer
. 2020 Mar;
8(1).
PMID: 32169869
Background: Neuroblastoma (NB) is a childhood cancer for which new treatment options are needed. The success of immune checkpoint blockade in the treatment of adult solid tumors has prompted the...
8.
Knight F, Gilchuk P, Kumar A, Becker K, Sevimli S, Jacobson M, et al.
ACS Nano
. 2019 Sep;
13(10):10939-10960.
PMID: 31553872
Tissue-resident memory T cells (T) patrol nonlymphoid organs and provide superior protection against pathogens that commonly infect mucosal and barrier tissues, such as the lungs, intestine, liver, and skin. Thus,...
9.
Baljon J, Dandy A, Wang-Bishop L, Wehbe M, Jacobson M, Wilson J
Biomater Sci
. 2019 Apr;
7(5):2200.
PMID: 30977488
Correction for 'The efficiency of cytosolic drug delivery using pH-responsive endosomolytic polymers does not correlate with activation of the NLRP3 inflammasome' by Jessalyn J. Baljon et al., Biomater. Sci., 2019,...
10.
Baljon J, Dandy A, Wang-Bishop L, Wehbe M, Jacobson M, Wilson J
Biomater Sci
. 2019 Mar;
7(5):1888-1897.
PMID: 30843539
Inefficient cytosolic delivery has limited the development of many promising biomacromolecular drugs, a long-standing challenge that has prompted extensive development of drug carriers that facilitate endosomal escape. Although many such...