Lifu Sheng
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Explore the profile of Lifu Sheng including associated specialties, affiliations and a list of published articles.
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12
Citations
472
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Recent Articles
1.
Gao Y, Zhu J, Li J, Peng X, Nie X, Zhao H, et al.
Postgrad Med J
. 2025 Jan;
PMID: 39850008
Purpose: Endoscopic submucosal dissection (ESD) is currently one of the most curative treatments for early esophageal cancer. We conducted a retrospective case analysis to identify the characteristics of early esophageal...
2.
Yang Y, Stewart T, Zhang C, Wang P, Xu Z, Jin J, et al.
Mov Disord
. 2023 Oct;
39(1):40-52.
PMID: 37798868
Background: Progressive spreading of α-synuclein via gut-brain axis has been hypothesized in the pathogenesis of Parkinson's disease (PD). However, the source of seeding-capable α-synuclein in the gastrointestinal tract (GIT) has...
3.
Yu Z, Yang Y, Chan R, Shi M, Stewart T, Huang Y, et al.
CNS Neurosci Ther
. 2023 Aug;
30(2):e14393.
PMID: 37563872
Rationale: Synucleinopathies, including Parkinson's disease (PD), multiple system atrophy (MSA), and dementia with Lewy bodies (DLB), share a distinct pathological feature, that is, a widespread accumulation of α-synuclein (α-syn) in...
4.
Hong Z, Tian C, Stewart T, Aro P, Soltys D, Bercow M, et al.
Neurology
. 2021 May;
96(18):e2332-e2345.
PMID: 34032594
Objective: To develop a reliable and fast assay to quantify the α-synuclein (α-syn)-containing extracellular vesicles (EVs) in CSF and to assess their diagnostic potential for Parkinson disease (PD). Methods: A...
5.
Li N, Stewart T, Sheng L, Shi M, Cilento E, Wu Y, et al.
J Neuroinflammation
. 2020 Sep;
17(1):272.
PMID: 32943057
Background: Microglial function is vital for maintaining the health of the brain, and their activation is an essential component of neurodegeneration. There is significant research on factors that provoke "reactive"...
6.
Sheng L, Stewart T, Yang D, Thorland E, Soltys D, Aro P, et al.
Acta Neuropathol Commun
. 2020 Jul;
8(1):102.
PMID: 32641150
Parkinson's disease is a neurodegenerative disorder characterized by the transmission and accumulation of toxic species of α-synuclein (α-syn). Extracellular vesicles (EVs) are believed to play a vital role in the...
7.
Russell A, Sneider A, Witwer K, Bergese P, Bhattacharyya S, Cocks A, et al.
J Extracell Vesicles
. 2019 Nov;
8(1):1684862.
PMID: 31762963
Paracrine and endocrine roles have increasingly been ascribed to extracellular vesicles (EVs) generated by multicellular organisms. Central to the biogenesis, content, and function of EVs are their delimiting lipid bilayer...
8.
Shi M, Sheng L, Stewart T, Zabetian C, Zhang J
Prog Neurobiol
. 2019 Jan;
175:96-106.
PMID: 30685501
Extracellular vesicles (EVs), including exosomes and (shedding) microvesicles, are released by nearly all cell types and carry a cargo of proteins and nucleic acids that varies by the cell of...
9.
Cilento E, Jin L, Stewart T, Shi M, Sheng L, Zhang J
J Neurochem
. 2018 Nov;
151(4):397-416.
PMID: 30474862
Accurate, reliable, and objective biomarkers for Alzheimer's disease (AD), Parkinson's disease (PD), and related age-associated neurodegenerative disorders are urgently needed to assist in both diagnosis, particularly at early stages, and...
10.
Sheng L, Leshchynska I, Sytnyk V
Cereb Cortex
. 2018 Mar;
29(4):1439-1459.
PMID: 29522129
The neural cell adhesion molecule 2 (NCAM2) is encoded by a gene on chromosome 21 in humans. NCAM2 accumulates in synapses, but its role in regulation of synapse formation remains...