Lici A Schurig-Briccio
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Explore the profile of Lici A Schurig-Briccio including associated specialties, affiliations and a list of published articles.
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19
Citations
423
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Recent Articles
1.
Song J, Malwal S, Baig N, Schurig-Briccio L, Gao Z, Vaidya G, et al.
ACS Infect Dis
. 2020 Oct;
6(11):2979-2993.
PMID: 33085463
-prenyltransferases such as undecaprenyl diphosphate synthase (UPPS) and decaprenyl diphosphate synthase (DPPS) are essential enzymes in bacteria and are involved in cell wall biosynthesis. UPPS and DPPS are absent in...
2.
Schurig-Briccio L, Parraga Solorzano P, Lencina A, Radin J, Chen G, Sauer J, et al.
EMBO Rep
. 2020 Mar;
21(5):e45832.
PMID: 32202364
The success of Staphylococcus aureus as a pathogen is due to its capability of fine-tuning its cellular physiology to meet the challenges presented by diverse environments, which allows it to...
3.
Lencina A, Gennis R, Schurig-Briccio L
Biochim Biophys Acta Bioenerg
. 2019 Dec;
1861(2):148132.
PMID: 31816290
Sulfide:quinone oxidoreductase (SQR) is a monotopic membrane flavoprotein present in all domains of life, with multiple roles including sulfide detoxification, homeostasis and energy generation by providing electrons to respiratory or...
4.
Lencina A, Koepke J, Preu J, Muenke C, Gennis R, Michel H, et al.
Biochim Biophys Acta Bioenerg
. 2019 Sep;
1860(11):148080.
PMID: 31520616
The crystal structure of the enzyme previously characterized as a type-2 NADH:menaquinone oxidoreductase (NDH-2) from Thermus thermophilus has been solved at a resolution of 2.9 Å and revealed that this...
5.
Lencina A, Franza T, Sullivan M, Ulett G, Ipe D, Gaudu P, et al.
mBio
. 2018 Jul;
9(4).
PMID: 29970468
The opportunistic pathogen is the major cause of meningitis and sepsis in a newborn's first week, as well as a considerable cause of pneumonia, urinary tract infections, and sepsis in...
6.
Hards K, McMillan D, Schurig-Briccio L, Gennis R, Lill H, Bald D, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(28):7326-7331.
PMID: 29941569
Bedaquiline (BDQ), an inhibitor of the mycobacterial FF-ATP synthase, has revolutionized the antitubercular drug discovery program by defining energy metabolism as a potent new target space. Several studies have recently...
7.
Hammer N, Schurig-Briccio L, Gerdes S, Gennis R, Skaar E
mBio
. 2016 Jul;
7(4).
PMID: 27406563
Unlabelled: Staphylococcus aureus is the leading cause of skin and soft tissue infections, bacteremia, osteomyelitis, and endocarditis in the developed world. The ability of S. aureus to cause substantial disease...
8.
Feng X, Zhu W, Schurig-Briccio L, Lindert S, Shoen C, Hitchings R, et al.
Proc Natl Acad Sci U S A
. 2015 Dec;
112(51):E7073-82.
PMID: 26644565
There is a growing need for new antibiotics. Compounds that target the proton motive force (PMF), uncouplers, represent one possible class of compounds that might be developed because they are...
9.
Jackson J, Leung J, Stout C, Schurig-Briccio L, Gennis R
FEBS Lett
. 2015 Jul;
589(16):2027-33.
PMID: 26143375
The membrane protein transhydrogenase in animal mitochondria and bacteria couples reduction of NADP⁺ by NADH to proton translocation. Recent X-ray data on Thermus thermophilus transhydrogenase indicate a significant difference in...
10.
Leung J, Schurig-Briccio L, Yamaguchi M, Moeller A, Speir J, Gennis R, et al.
Science
. 2015 Jan;
347(6218):178-81.
PMID: 25574024
NADPH/NADP(+) (the reduced form of NADP(+)/nicotinamide adenine dinucleotide phosphate) homeostasis is critical for countering oxidative stress in cells. Nicotinamide nucleotide transhydrogenase (TH), a membrane enzyme present in both bacteria and...