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Liat Bar-On

Explore the profile of Liat Bar-On including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 647
Followers 0
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Recent Articles
1.
Yahalom-Ronen Y, Melamed S, Politi B, Erez N, Tamir H, Bar-On L, et al.
Vaccines (Basel) . 2024 May; 12(5). PMID: 38793742
The emergence of rapidly spreading variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) poses a major challenge to vaccines' protective efficacy. Intramuscular (IM) vaccine administration induces short-lived immunity but...
2.
Bar-On L, Dekel H, Aftalion M, Chitlaru T, Erez N
PLoS One . 2023 Dec; 18(12):e0294176. PMID: 38150441
SARS-CoV-2 infection elicits robust CD8 T-cell responses, yet the identity of the mechanisms playing dominant roles in initiating the virus-specific CD8 T-cell responses are largely unknown. In the present study,...
3.
Erez N, Achdout H, Yahalom-Ronen Y, Adutler-Lieber S, Bar-On L, Bar-Haim E, et al.
Curr Issues Mol Biol . 2023 Oct; 45(10):7944-7955. PMID: 37886945
Following viral infection, T-cells are crucial for an effective immune response to intracellular pathogens, including respiratory viruses. During the COVID-19 pandemic, diverse assays were required in pre-clinical trials to evaluate...
4.
Bar-On L, Aftalion M, Makdasi E, Gur D, Alcalay R, Cohen H, et al.
Vaccines (Basel) . 2022 Apr; 10(4). PMID: 35455362
Longevity of the immune response following viral exposure is an essential aspect of SARS-CoV-2 infection. Mild SARS-CoV-2 infection of K18-hACE2 mice was implemented for evaluating the mounting and longevity of...
5.
Chitlaru T, Bar-Haim E, Bar-On L, Rotem S, Cohen H, Elia U, et al.
Pathogens . 2021 Aug; 10(8). PMID: 34451403
HLA transgenic mice are instrumental for evaluation of human-specific immune responses to viral infection. Mice do not develop COVID-19 upon infection with SARS-CoV-2 due to the strict tropism of the...
6.
Falach R, Bar-On L, Lazar S, Kadar T, Mazor O, Aftalion M, et al.
JCI Insight . 2021 May; 6(12). PMID: 33974566
Mice are normally unaffected by SARS coronavirus 2 (SARS-CoV-2) infection since the virus does not bind effectively to the murine version of the angiotensin-converting enzyme 2 (ACE2) receptor molecule. Here,...
7.
Makdasi E, Levy Y, Alcalay R, Noy-Porat T, Zahavy E, Mechaly A, et al.
Viruses . 2021 Apr; 13(4). PMID: 33810465
Monoclonal antibodies represent an important avenue for COVID-19 therapy and are routinely used for rapid and accessible diagnosis of SARS-CoV-2 infection. The recent emergence of SARS-CoV-2 genetic variants emphasized the...
8.
Bar-On L, Cohen H, Elia U, Rotem S, Bercovich-Kinori A, Bar-Haim E, et al.
Vaccine . 2017 Nov; 35(50):7001-7009. PMID: 29102170
Francisella tularensis is the intracellular bacterial pathogen causing the respiratory life-threatening disease tularemia. Development of tularemia vaccines has been hampered by an incomplete understanding of the correlates of immunity. Moreover,...
9.
Zlotnikov-Klionsky Y, Nathansohn-Levi B, Shezen E, Rosen C, Kagan S, Bar-On L, et al.
Immunity . 2015 Sep; 43(4):776-87. PMID: 26384546
Emerging evidence suggests that immunological mechanisms underlie metabolic control of adipose tissue. Here, we have shown the regulatory impact of a rare subpopulation of dendritic cells, rich in perforin-containing granules...
10.
Rotem S, Cohen O, Bar-Haim E, Bar-On L, Ehrlich S, Shafferman A
PLoS One . 2014 Jan; 9(1):e85215. PMID: 24400128
Recently we described an unbiased bacterial whole-genome immunoinformatic analysis aimed at selection of potential CTL epitopes located in "hotspots" of predicted MHC-I binders. Applying this approach to the proteome of...