Lianrong Wang
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Explore the profile of Lianrong Wang including associated specialties, affiliations and a list of published articles.
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64
Citations
2351
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Recent Articles
11.
Li J, Cheng R, Wang Z, Yuan W, Xiao J, Zhao X, et al.
Nature
. 2024 Mar;
629(8011):467-473.
PMID: 38471529
Prokaryotes have evolved intricate innate immune systems against phage infection. Gabija is a highly widespread prokaryotic defence system that consists of two components, GajA and GajB. GajA functions as a...
12.
Wu M, Xu X, Hu R, Chen Q, Chen L, Yuan Y, et al.
Adv Sci (Weinh)
. 2023 Oct;
10(35):e2207736.
PMID: 37875397
Candida albicans (C. albicans), a ubiquitous polymorphic fungus in humans, causes different types of candidiasis, including oral candidiasis (OC) and vulvovaginal candidiasis (VVC), which are physically and mentally concerning and...
13.
Xie B, Gao D, Zhou B, Chen S, Wang L
J Pharm Anal
. 2023 Aug;
13(7):711-725.
PMID: 37577385
Single-cell multi-Omics (SCM-Omics) and spatial multi-Omics (SM-Omics) technologies provide state-of-the-art methods for exploring the composition and function of cell types in tissues/organs. Since its emergence in 2009, single-cell RNA sequencing...
14.
Jiang S, Chen K, Wang Y, Zhang Y, Tang Y, Huang W, et al.
mBio
. 2023 Jun;
14(4):e0093323.
PMID: 37260233
DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome. Usually, this modification gene cluster is paired with...
15.
Wang Y, Miao Z, Xu C, Cai Y, Yang Y, Hu Y, et al.
Cell Death Dis
. 2023 May;
14(5):325.
PMID: 37179386
The common pathogenesis of Alzheimer's disease (AD) and Parkinson's disease (PD) has been supported by biochemical, genetic and molecular evidence. Mitochondrial dysfunction is considered to be the common pathology in...
16.
Xu C, Rao J, Xie Y, Lu J, Li Z, Dong C, et al.
Microbiol Spectr
. 2023 Jan;
11(1):e0350922.
PMID: 36598279
Bacterial defense barriers, such as DNA methylation-associated restriction-modification (R-M) and the CRISPR-Cas system, play an important role in bacterial antimicrobial resistance (AMR). Recently, a novel R-M system based on DNA...
17.
Wu M, Chen L, Chen Q, Hu R, Xu X, Wang Y, et al.
Adv Mater
. 2022 Nov;
35(6):e2208578.
PMID: 36440662
Sepsis, a widely recognized disease, is characterized by multiple pathogen infections. Therefore, it is imperative to develop methods that can efficiently identify and neutralize pathogen species. Phage cocktail therapy utilizes...
18.
Zheng W, Wang K, Wu Y, Yan G, Zhang C, Li Z, et al.
Theranostics
. 2022 Nov;
12(17):7289-7306.
PMID: 36438488
A hexanucleotide repeat expansion (GGGGCC) is the most common genetic origin of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Haploinsufficiency of C9orf72 has been proposed as a possible disease...
19.
Gao H, Gong X, Zhou J, Zhang Y, Duan J, Wei Y, et al.
Nat Commun
. 2022 Nov;
13(1):6773.
PMID: 36351933
DNA phosphorothioate (PT) modification, with a nonbridging phosphate oxygen substituted by sulfur, represents a widespread epigenetic marker in prokaryotes and provides protection against genetic parasites. In the PT-based defense system...
20.
Zou X, Xiao X, Mo Z, Ge Y, Jiang X, Huang R, et al.
Nat Commun
. 2022 Aug;
13(1):4491.
PMID: 35918338
Phages are regarded as powerful antagonists of bacteria, especially in industrial fermentation processes involving bacteria. While bacteria have developed various defense mechanisms, most of which are effective against a narrow...