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Lianhong Pan

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Articles 18
Citations 336
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Recent Articles
1.
Feng F, Wu J, Chi Q, Wang S, Liu W, Yang L, et al.
Adv Sci (Weinh) . 2024 Aug; 11(38):e2405975. PMID: 39099416
Lactate plays a critical role as an energy substrate, metabolite, and signaling molecule in hepatocellular carcinoma (HCC). Intracellular lactate-derived protein lysine lactylation (Kla) is identified as a contributor to the...
2.
Wang S, Han J, Wang Z, Liu X, Wang C, Nisar M, et al.
Curr Comput Aided Drug Des . 2024 May; PMID: 38818918
A malignant tumor is a frequent and common disease that severely threatens human health. Many mechanisms, such as cell signaling pathway, anti-apoptosis mechanism, cell stemness, metabolism, and cell phenotype, have...
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Wang Z, Li L, Wang S, Wei J, Qu L, Pan L, et al.
Front Pharmacol . 2022 Dec; 13:1025860. PMID: 36452234
Cancer is the second leading cause of elevated mortality worldwide. Thus, the development of drugs and treatments is needed to enhance the survival rate of the cancer-affected population. Recently, gut...
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Feng F, Pan L, Wu J, Liu M, He L, Yang L, et al.
Front Pharmacol . 2022 Nov; 13:1019486. PMID: 36425581
Schisantherin A (STA) is a traditional Chinese medicine extracted from the plant , which has a wide range of anti-inflammatory, antioxidant, and other pharmacological effects. This study investigates the anti-hepatocellular...
6.
Feng F, Liu M, Pan L, Wu J, Wang C, Yang L, et al.
Front Pharmacol . 2022 May; 13:906212. PMID: 35614943
Keloids are fibroproliferative skin disorder caused by abnormal healing of injured or irritated skin and are characterized by excessive extracellular matrix (ECM) synthesis and deposition, which results in excessive collagen...
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Pan L, Feng F, Wu J, Fan S, Han J, Wang S, et al.
Pharmacol Res . 2022 May; 181:106270. PMID: 35605812
Cancer stem cells drive tumor initiation, progression, and recurrence, which compromise the effectiveness of anti-tumor drugs. Here, we report that demethylzeylasteral (DML), a triterpene anti-tumor compound, suppressed tumorigenesis of liver...
8.
Feng F, Pan L, Wu J, Li L, Xu H, Yang L, et al.
Int J Biol Sci . 2021 Nov; 17(15):4340-4352. PMID: 34803502
Cepharanthine (CEP), a natural compound extracted from Hayata, has been found to have the potential to treat a variety of tumors in recent years. This study aims to evaluate the...
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Pan L, Feng F, Wu J, Li L, Xu H, Yang L, et al.
Food Funct . 2021 Nov; 12(23):12036-12046. PMID: 34755740
Diosmetin (DSM), a newly discovered natural flavonoid, found in citrus plants and olive leaves, has been reported to inhibit the progression of cancer when used as a food supplement. This...
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Wu J, Qian Y, Chen C, Feng F, Pan L, Yang L, et al.
Front Pharmacol . 2021 Oct; 12:735087. PMID: 34603050
This study aimed to determine whether hesperetin (HPT) has chondroprotective effects against the TNF-α-induced inflammatory response of chondrocytes and related mechanisms and clarify the impact of HPT on osteoarthritis (OA)...