Liang-Wu Fu
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Explore the profile of Liang-Wu Fu including associated specialties, affiliations and a list of published articles.
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31
Citations
434
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Recent Articles
11.
Guo Z, Longhurst J, Tjen-A-Looi S, Fu L
Am J Physiol Regul Integr Comp Physiol
. 2016 May;
311(2):R410-25.
PMID: 27225950
The external lateral parabrachial nucleus (elPBN) within the pons and rostral ventrolateral medulla (rVLM) contributes to central processing of excitatory cardiovascular reflexes during stimulation of cardiac sympathetic afferent nerves (CSAN)....
12.
Tjen-A-Looi S, Guo Z, Fu L, Longhurst J
Sci Rep
. 2016 May;
6:25910.
PMID: 27181844
The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN. Parvocellular PVN neurons project to sympathoexcitatory cardiovascular regions of the rostral...
13.
Fu L, Longhurst J
Am J Physiol Heart Circ Physiol
. 2013 May;
305(1):H76-85.
PMID: 23645463
Thinly myelinated Aδ-fiber and unmyelinated C-fiber cardiac sympathetic (spinal) sensory nerve fibers are activated during myocardial ischemia to transmit the sensation of angina pectoris. Although recent observations showed that myocardial...
14.
Fu L, Guo Z, Longhurst J
Am J Physiol Heart Circ Physiol
. 2012 Jan;
302(7):H1444-53.
PMID: 22268111
Stimulation of cardiac sympathetic afferents during myocardial ischemia with metabolites such as bradykinin (BK) evokes sympathoexcitatory reflex responses and activates neurons in the external lateral parabrachial nucleus (elPBN). The present...
15.
Fu L, Longhurst J
Am J Physiol Heart Circ Physiol
. 2010 Sep;
299(6):H1762-71.
PMID: 20870803
Myocardial ischemia activates cardiac sympathetic afferents leading to chest pain and reflex cardiovascular responses. Brief myocardial ischemia leads to ATP release in the interstitial space. Furthermore, exogenous ATP and α,β-methylene...
16.
Fu L, Guo Z, Longhurst J
J Physiol
. 2010 May;
588(Pt 13):2473-86.
PMID: 20442267
Myocardial ischaemia activates cardiac sympathetic afferents leading to chest pain and reflex cardiovascular responses. Previous studies have shown that a brief period of myocardial ischaemia increases endothelin in cardiac venous...
17.
Fu L, Longhurst J
Am J Physiol Heart Circ Physiol
. 2009 Nov;
298(1):H235-44.
PMID: 19897709
Myocardial ischemia is a complex process leading to the simultaneous release of a number of mediators, including thromboxane A(2) (TxA(2)) and bradykinin (BK), that activate cardiac spinal afferents. The present...
18.
Guo Z, Tjen-A-Looi S, Fu L, Longhurst J
Am J Physiol Heart Circ Physiol
. 2009 Aug;
297(4):H1478-86.
PMID: 19684188
Our previous studies have shown that nitric oxide (NO) synthase (NOS)-containing neurons in the rostral ventrolateral medulla (rVLM) are activated during cardiac sympathoexcitatory reflexes (Refs. 12 and 13). However, the...
19.
Fu L, Longhurst J
Handb Exp Pharmacol
. 2009 Aug;
(194):185-225.
PMID: 19655108
The heart at the time of Sir William Harvey originally was thought to be an insensate organ. Today, however, we know that this organ is innervated by sensory nerves that...
20.
Fu L, Longhurst J
J Appl Physiol (1985)
. 2009 Apr;
106(6):1800-9.
PMID: 19359606
Previous studies have demonstrated that electroacupuncture (EA) attenuates sympathoexcitatory reflex responses by activating a long-loop pathway involving the hypothalamic arcuate nucleus (ARC), midbrain ventrolateral periaqueductal gray (vlPAG), and rostral ventrolateral...