Liang-Liang Cai
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Explore the profile of Liang-Liang Cai including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
128
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Recent Articles
1.
Huang W, Ye H, Cai L, Ma Q, Lu C, Tong S, et al.
Front Genet
. 2019 Aug;
10:615.
PMID: 31396257
Leukoaraiosis (LA) is shown as white matter hyperintensities on T2-weighted magnetic resonance imaging brain scans. Together with candidate gene association studies (CGAS), multiple genome-wide association studies (GWAS) have reported large...
2.
Cai L, Wang J
Oncol Lett
. 2019 Jun;
17(6):4751-4760.
PMID: 31186680
The recent successful use of the immune checkpoint inhibitors (CPIs) anti-programmed death receptor-1 (PD-1)/PD-1 ligand 1 in clinical trials indicates their crucial role in obtaining an effective cancer immune therapy....
3.
Zhao Y, Cai L, Wang H, Shi X, Ye H, Song P, et al.
Onco Targets Ther
. 2019 Apr;
12:2343-2353.
PMID: 30992671
Background: Vitamin D has been known to have an anticancer effect, but the mechanisms underlying this is poorly explored. The present study aimed to investigate the antitumor role of vitamin...
4.
Huang W, Yi K, Li Z, Wang H, Li M, Cai L, et al.
Front Aging Neurosci
. 2018 Jun;
10:143.
PMID: 29875652
Leukoaraiosis (LA) is neuroimaging abnormalities of the cerebral white matter in elderly people. However, the molecular mechanisms underlying the cerebral white matter lesions remain unclear. Here, we reported an epigenetic...
5.
Cai L, Huang W, Su Z, Ye H, Wang L, Wu Y, et al.
Sci Rep
. 2017 Dec;
7(1):17379.
PMID: 29234073
Warfarin is a commonly prescribed and effective oral anticoagulant. Genetic polymorphisms associated with warfarin metabolism and sensitivity have been implicated in the wide inter-individual dose variation that is observed. Several...
6.
Incidence and risk factors of leukoaraiosis from 4683 hospitalized patients: A cross-sectional study
Lin Q, Huang W, Ma Q, Lu C, Tong S, Ye J, et al.
Medicine (Baltimore)
. 2017 Sep;
96(39):e7682.
PMID: 28953609
Leukoaraiosis (LA) refers to white matter hyperintensities or white matter lesions (WMLs) on magnetic resonance imaging (MRI) scans of the brain; this disease is associated with an increased risk of...
7.
Huang W, Lu C, Zhang Y, Yi K, Cai L, Li M, et al.
Front Aging Neurosci
. 2016 Oct;
8:220.
PMID: 27708576
Cerebral cavernous malformations (CCMs) are common vascular malformations that predominantly arise in the central nervous system and are mainly characterized by enlarged vascular cavities without intervening brain parenchyma. Familial CCMs...
8.
Cai L, Liu G, Tzeng C
Medicine (Baltimore)
. 2016 Sep;
95(35):e4695.
PMID: 27583899
Background: During development, methylation permanently changes gene activity, while aberrant gene methylation is key to human tumorigenesis. Gene methylation is an epigenetic event leading to gene silencing and some tumor...
9.
Huang W, Ye H, Li F, Yi K, Zhang Y, Cai L, et al.
Medicine (Baltimore)
. 2016 Sep;
95(35):e3857.
PMID: 27583843
Leukoaraiosis (LA) is a frequent neuroimaging finding commonly observed on brain MRIs of elderly people with prevalence ranging from 50% to 100%. Multiple susceptibility genes or genetic risk factors for...
10.
Cai L, Ye H, Zheng L, Ruan R, Tzeng C
Curr Drug Targets
. 2014 Sep;
15(10):965-72.
PMID: 25182470
Circulating tumor cells (CTCs) have attracted interest as biomarkers of cancer metastases but only recently has a reliable method of CTC detection been developed. CTCs can be thought of as...