Leyllane Rafael Moreira
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Explore the profile of Leyllane Rafael Moreira including associated specialties, affiliations and a list of published articles.
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13
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21
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Recent Articles
1.
Oliveira K, Torres D, Barros M, Rafael Moreira L, Junior C, Soares A, et al.
Immun Inflamm Dis
. 2024 Sep;
12(9):e1330.
PMID: 39267468
Introduction: Chagas disease is caused by the protozoan Trypanosoma cruzi and is clinically divided into acute and chronic phases. Chronic Chagas cardiomyopathy is the most studied manifestation of the disease....
2.
da Silva A, Rafael Moreira L, Oliveira C, Junior C, O K, Oliveira K, et al.
Mol Biochem Parasitol
. 2024 Apr;
258:111618.
PMID: 38588892
Trypanosoma cruzi is a parasite with a high capacity to adapt to the host. Animal models have already demonstrated that the tropism of this parasite occurs not only in cardiac/digestive...
3.
Rafael Moreira L, Silva A, da Costa-Oliveira C, da Silva-Junior C, Oliveira K, Torres D, et al.
Front Immunol
. 2024 Mar;
15:1280877.
PMID: 38533504
Background/introduction: Adipose tissue (AT) has been highlighted as a promising reservoir of infection for viruses, bacteria and parasites. Among them is , which causes Chagas disease. The recommended treatment for...
4.
Torres D, Oliveira K, Barros M, Rafael Moreira L, de Freitas Firmino L, de Albuquerque M, et al.
Parasite Immunol
. 2024 Feb;
46(2):e13024.
PMID: 38385576
Studies involving the immune response in Chagas disease suggest an imbalance in the immune response of symptomatic patients, with an inflammatory profile dominating in Chagas heart disease, mainly by tumour...
5.
Rafael Moreira L, Silva A, Oliveira C, Junior C, Nascimento A, Oliveira K, et al.
Mem Inst Oswaldo Cruz
. 2023 Oct;
118:e220295.
PMID: 37878830
Background: Trypanosoma cruzi, which causes Chagas disease (CD), is a versatile haemoparasite that uses several strategies to evade the host's immune response, including adipose tissue (AT), used as a reservoir...
6.
Rafael Moreira L, Oliveira K, Torres D, Barros M, de Arruda T, Nascimento A, et al.
Parasite Immunol
. 2023 Apr;
45(6):e12983.
PMID: 37066749
Benznidazole (Bz) is the recommended drug for the treatment of Chagas disease; however, its efficacy may vary according to the sensitivity of Trypanosoma cruzi strains to the drug and host...
7.
da Costa-Oliveira C, Paiva-Cavalcanti M, Barros M, Nakazawa M, Melo M, Pessoa-E-Silva R, et al.
Exp Parasitol
. 2023 Feb;
247:108478.
PMID: 36731642
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi (T. cruzi), affects millions of people worldwide. Polymerase Chain Reaction (PCR) and real-time quantitative PCR (qPCR) have been used as tools...
8.
Junior J, da Silva A, Oliveira K, Rafael Moreira L, Caires S, da Silva A, et al.
Nat Prod Res
. 2023 Jan;
38(13):2329-2335.
PMID: 36661179
Due to the limitations of Chagas disease therapy, microalgae can be promising in the search of new trypanocidal compounds, since these organisms produce bioactive compounds with large pharmaceutical applications, including...
9.
Torres D, de Arruda T, Barros M, Goncales J, Soares A, Oliveira K, et al.
Immunobiology
. 2021 Dec;
227(1):152166.
PMID: 34936965
Soluble TNF receptors (sTNFR1 and sTNFR2) are natural endogenous inhibitors of TNF and are elevated in inflammatory, autoimmune, and chronic degenerative diseases. In Chagas disease, pleiotropic cytokine TNF is considered...
10.
Nova I, Rafael Moreira L, Torres D, Oliveira K, de Siqueira Patriota L, Coelho L, et al.
Antibiotics (Basel)
. 2020 Aug;
9(8).
PMID: 32823803
causes the lethal Chagas disease, which is endemic in Latin America. Flowers of (Moringaceae) express a trypsin inhibitor (MoFTI) whose toxicity to trypomastigotes was previously reported. Here, we studied the...