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Lewis R Roberts

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Articles 361
Citations 19072
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Recent Articles
1.
Danpanichkul P, Suparan K, Auttapracha T, Tothanarungroj P, Kongarin S, Rakwong K, et al.
Mayo Clin Proc . 2025 Feb; PMID: 39945699
Objective: To explore the increasing incidence of gastrointestinal (GI) cancers and related risk factors in younger patients. Patient And Methods: We used data from the Global Burden of Disease Study...
2.
Tesfay M, Zhang Y, Ferdous K, Taylor M, Cios A, Shelton R, et al.
Mol Ther Oncol . 2025 Jan; 32(4):200913. PMID: 39758249
Members of the genus including Jurona virus (JURV) have emerged as promising immunotherapeutic agents, characterized by their tumor selectivity, fast kinetics, low seroprevalence, and minimal toxicity in humans. Here, we...
3.
Kim K, Zheng Y, Joyce B, Nannini D, Wang J, Qu Y, et al.
Hepatol Int . 2024 Dec; PMID: 39704909
Background: People living with the human immunodeficiency virus (HIV) are at a greater risk of developing hepatocellular carcinoma (HCC), potentially due to the stimulation of inflammation by HIV infection. Inflammation-related...
4.
Jorgenson L, Torbenson M, Halfdanarson T, Kankeu Fonkoua L, Tran N, Roberts L, et al.
Front Nucl Med . 2024 Dec; 4:1480471. PMID: 39664608
Purpose: The aims of this study were to evaluate and compare fibroblast activation protein (FAP) expression and localization in surgically resected cholangiocarcinoma (CCA), primary and metastatic hepatocellular carcinoma (HCC), hepatocellular...
5.
Roberts L
Clin Liver Dis . 2024 Nov; 29(1):17-31. PMID: 39608955
This article reviews surveillance for the detection of early stage hepatocellular carcinoma, covering the rationale for surveillance, optimal selection of persons needing surveillance, methods and frequency of screening, strategies for...
6.
Antwi S, Siaw A, Armasu S, Frank J, Yan I, Ahmed F, et al.
medRxiv . 2024 Nov; PMID: 39606355
Background And Aims: Metabolic liver disease is the fastest rising cause of hepatocellular carcinoma (HCC) worldwide, but the underlying molecular processes that drive HCC development in the setting of metabolic...
7.
Fujiwara N, Lopez C, Marsh T, Raman I, Marquez C, Paul S, et al.
Gastroenterology . 2024 Nov; 168(3):556-567.e7. PMID: 39521255
Background & Aims: Hepatocellular carcinoma (HCC) risk stratification is an urgent unmet need for cost-effective HCC screening and early detection in patients with cirrhosis to improve poor HCC prognosis. Methods:...
8.
Aggarwal M, Simadibrata D, Kipp B, Prokop L, Barr Fritcher E, Schneider A, et al.
J Clin Med . 2024 Nov; 13(21). PMID: 39518600
: This systematic review and meta-analysis aims to compare the performance of UroVysion FISH based on the different definitions of a positive result used in published literature with the goal...
9.
Nishimura S, Linares J, LHermitte A, Duran A, Cid-Diaz T, Martinez-Ordonez A, et al.
Mol Cell . 2024 Oct; 84(23):4660-4676.e10. PMID: 39423823
Hepatocellular carcinoma (HCC) emerges from chronic inflammation, to which activation of hepatic stellate cells (HSCs) contributes by shaping a pro-tumorigenic microenvironment. Key to this process is p62, whose inactivation leads...
10.
Nartey Y, Yang J, Zemla T, Ayawin J, Asibey S, El-Kassas M, et al.
Cancer Res Commun . 2024 Sep; 4(10):2653-2659. PMID: 39324700
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide including sub-Saharan Africa. The GALAD score, derived from Gender, Age, Lens culinaris agglutinin-reactive fraction of alpha fetoprotein,...