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Lev Levanov

Explore the profile of Lev Levanov including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2057
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Recent Articles
1.
Kedari A, Iheozor-Ejiofor R, Salminen P, Ugurlu H, Makela A, Levanov L, et al.
Structure . 2024 Oct; 32(12):2220-2230.e4. PMID: 39471803
Host-cell entry of the highly pathogenic rabies virus (RABV) is mediated by glycoprotein (G) spikes, which also comprise the primary target for the humoral immune response. RABV glycoprotein (RABV-G) displays...
2.
Tuomisto L, Virtanen J, Kegler K, Levanov L, Sukura A, Sironen T, et al.
Vet Med Sci . 2024 Jan; 10(1):e1342. PMID: 38227707
Background: Squamous cell carcinoma is the most common genital, ocular and gastric tumour in horses. Equus caballus papillomavirus type 2 (EcPV2) DNA has been detected in several studies in equine...
3.
Plyusnin A, Kedari A, Rissanen I, Iheozor-Ejiofor R, Lundkvist A, Vapalahti O, et al.
J Gen Virol . 2023 Oct; 104(10). PMID: 37801017
Identification of B-cell epitopes facilitates the development of vaccines, therapeutic antibodies and diagnostic tools. Previously, the binding site of the bank vole monoclonal antibody (mAb) 4G2 against Puumala virus (PUUV,...
4.
Pietiainen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, et al.
Cell Rep Methods . 2023 Sep; 3(8):100565. PMID: 37671026
We present a miniaturized immunofluorescence assay (mini-IFA) for measuring antibody response in patient blood samples. The method utilizes machine learning-guided image analysis and enables simultaneous measurement of immunoglobulin M (IgM),...
5.
Makela A, Ugurlu H, Hannula L, Kant R, Salminen P, Fagerlund R, et al.
Nat Commun . 2023 Mar; 14(1):1637. PMID: 36964125
The emergence of increasingly immunoevasive SARS-CoV-2 variants emphasizes the need for prophylactic strategies to complement vaccination in fighting the COVID-19 pandemic. Intranasal administration of neutralizing antibodies has shown encouraging protective...
6.
Oksanen L, Virtanen J, Sanmark E, Rantanen N, Venkat V, Sofieva S, et al.
Indoor Air . 2022 Oct; 32(10):e13118. PMID: 36305066
SARS-CoV-2 has been detected both in air and on surfaces, but questions remain about the patient-specific and environmental factors affecting virus transmission. Additionally, more detailed information on viral sampling of...
7.
Iheozor-Ejiofor R, Vapalahti K, Sironen T, Levanov L, Hepojoki J, Lundkvist A, et al.
Viruses . 2022 May; 14(5). PMID: 35632643
Nephropathia epidemica (NE), a mild form of haemorrhagic fever with renal syndrome (HFRS), is an acute febrile illness caused by Puumala orthohantavirus (PUUV). NE manifests typically with acute kidney injury...
8.
Fred S, Kuivanen S, Ugurlu H, Casarotto P, Levanov L, Saksela K, et al.
Front Pharmacol . 2022 Feb; 12:755600. PMID: 35126106
Repurposing of currently available drugs is a valuable strategy to tackle the consequences of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on SARS-CoV-2 in cell culture...
9.
Rusanen J, Kareinen L, Szirovicza L, Ugurlu H, Levanov L, Jaaskelainen A, et al.
mBio . 2021 May; 12(3). PMID: 34006662
The ongoing coronavirus disease 2019 (COVID-19) pandemic has seen an unprecedented increase in the demand for rapid and reliable diagnostic tools, leaving many laboratories scrambling for resources. We present a...
10.
Lin J, Tang C, Wei H, Du B, Chen C, Wang M, et al.
Cell Host Microbe . 2021 Feb; 29(3):489-502.e8. PMID: 33548198
The SARS-CoV-2 virus, the causative agent of COVID-19, is undergoing constant mutation. Here, we utilized an integrative approach combining epidemiology, virus genome sequencing, clinical phenotyping, and experimental validation to locate...