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» Authors » Letizia Vallino

Letizia Vallino

Explore the profile of Letizia Vallino including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 196
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Oncology
Top 10 Co-Authors
Ciro Isidoro
Alessandra Ferraresi
Chiara Vidoni
Danny N Dhanasekaran
Amreen Salwa
Beatrice Garavaglia
Andrea Esposito
Eleonora Secomandi
Carlo Girone
Gianluca Gaidano
Published In
Int J Mol Sci
Biomedicines
J Tradit Complement Med
Cells
Semin Cancer Biol
Affiliations
Soon will be listed here.
Recent Articles
1.
Probiotic-Derived Metabolites from OC01 Reprogram Tumor-Associated Macrophages to an Inflammatory Anti-Tumoral Phenotype: Impact on Colorectal Cancer Cell Proliferation and Migration
Garavaglia B, Vallino L, Ferraresi A, Amoruso A, Pane M, Isidoro C
Biomedicines . 2025 Feb; 13(2). PMID: 40002754
Tumor-associated macrophages (TAMs) are key players in the colorectal cancer (CRC) tumor microenvironment (TME), representing the most abundant immune cells within it. The interplay between the intestinal microbiota, macrophages, and...
2.
High Mitophagy and Low Glycolysis Predict Better Clinical Outcomes in Acute Myeloid Leukemias
Salwa A, Ferraresi A, Vallino L, Maheshwari C, Moia R, Gaidano G, et al.
Int J Mol Sci . 2024 Nov; 25(21). PMID: 39519080
Acute myeloid leukemia (AML) emerges as one of the most common and fatal leukemias. Treatment of the disease remains highly challenging owing to profound metabolic rewiring mechanisms that confer plasticity...
3.
Three-Dimensional Cell Cultures as a Feasible and Promising Alternative to Two-Dimensional and Animal Models in Cancer Research
Esposito A, Ferraresi A, Vallino L, Garavaglia B, Dhanasekaran D, Isidoro C
Int J Biol Sci . 2024 Oct; 20(13):5293-5311. PMID: 39430243
Cancer represents one of the diseases with the highest mortality rate worldwide. The burden of cancer continues to increase, not only affecting the health-related quality of life of patients but...
4.
Ovarian Cancer Cell-Conditioning Medium Induces Cancer-Associated Fibroblast Phenoconversion through Glucose-Dependent Inhibition of Autophagy
Ferraresi A, Girone C, Maheshwari C, Vallino L, Dhanasekaran D, Isidoro C
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38891879
One aspect of ovarian tumorigenesis which is still poorly understood is the tumor-stroma interaction, which plays a major role in chemoresistance and tumor progression. Cancer-associated fibroblasts (CAFs), the most abundant...
5.
Differential Competitive Growth of Transgenic Subclones of Neuroblastoma Cells Expressing Different Levels of Cathepsin D Co-Cultured in 2D and 3D in Response to EGF: Implications in Tumor Heterogeneity and Metastasis
Secomandi E, Esposito A, Camurani G, Vidoni C, Salwa A, Lualdi C, et al.
Cancers (Basel) . 2024 Apr; 16(7). PMID: 38611021
Neuroblastoma (NB) is an embryonal tumor arising from the sympathetic central nervous system. The epidermal growth factor (EGF) plays a role in NB growth and metastatic behavior. Recently, we have...
6.
Preclinical evidence for preventive and curative effects of resveratrol on xenograft cholangiocarcinogenesis
Thongchot S, Ferraresi A, Vidoni C, Salwa A, Vallino L, Kittirat Y, et al.
Cancer Lett . 2023 Dec; 582:216589. PMID: 38097133
Cholangiocarcinoma (CCA), the malignant tumor of bile duct epithelial cells, is a relatively rare yet highly lethal cancer. In this work, we tested the ability of Resveratrol (RV) to prevent...
7.
High Expression Negatively Correlates with Expression and Predicts Better Prognosis in Diffuse Large B-Cell Lymphoma: Role of Autophagy
Salwa A, Ferraresi A, Secomandi E, Vallino L, Moia R, Patriarca A, et al.
Cells . 2023 Aug; 12(15). PMID: 37566004
Diffuse large B-cell lymphoma (DLBCL) is characterized by high molecular and clinical heterogeneity. Autophagy, a lysosome-driven catabolic process devoted to macromolecular turnover, is fundamental in maintaining normal hematopoietic stem cells...
8.
Cell-free OC01 supernatant suppresses IL-6-induced proliferation and invasion of human colorectal cancer cells: Effect on β-Catenin degradation and induction of autophagy
Vallino L, Garavaglia B, Visciglia A, Amoruso A, Pane M, Ferraresi A, et al.
J Tradit Complement Med . 2023 Mar; 13(2):193-206. PMID: 36970462
Background And Aim: Gut microbiota is considered as a complex organ of human body. The interaction between the host and microbiota is dynamic and controlled by a huge number of...
9.
Glycolysis Inhibition of Autophagy Drives Malignancy in Ovarian Cancer: Exacerbation by IL-6 and Attenuation by Resveratrol
Vidoni C, Ferraresi A, Vallino L, Salwa A, Ha J, Seca C, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36675246
Cancer cells drive the glycolytic process towards the fermentation of pyruvate into lactate even in the presence of oxygen and functioning mitochondria, a phenomenon known as the "Warburg effect". Although...
10.
Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of and β-Catenin Mutational Status
Garavaglia B, Vallino L, Ferraresi A, Esposito A, Salwa A, Vidoni C, et al.
Biomedicines . 2022 May; 10(5). PMID: 35625868
Colorectal cancer (CRC) pathogenesis is mainly driven by alterations in WNT signaling, which results in altered transcriptional activity of β-Catenin. Mutations in (Adenomatous Polyposis Coli) are reflected in β-Catenin hyperactivation...