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Leslie Revoredo

Explore the profile of Leslie Revoredo including associated specialties, affiliations and a list of published articles. Areas
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Citations 203
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Recent Articles
1.
Liebschutz J, Subramaniam G, Stone R, Appleton N, Gelberg L, Lovejoy T, et al.
Addict Sci Clin Pract . 2023 Nov; 18(1):70. PMID: 37980494
Background: Preventing progression to moderate or severe opioid use disorder (OUD) among people who exhibit risky opioid use behavior that does not meet criteria for treatment with opioid agonists or...
2.
Stafylis C, Vavala G, Wang Q, McLeman B, Lemley S, Young S, et al.
JMIR Form Res . 2022 Sep; 6(9):e35648. PMID: 36149729
Background: Social media sites, dating apps, and information search sites have been used to reach individuals at high risk for HIV infection. However, it is not clear which platform is...
3.
Lemley S, Klausner J, Young S, Stafylis C, Mulatya C, Oden N, et al.
JMIR Res Protoc . 2020 Oct; 9(10):e20417. PMID: 33074164
Background: The majority of those living with HIV in the United States are men who have sex with men (MSM), and young, minority MSM account for more new HIV infections...
4.
May C, Ji S, Syed Z, Revoredo L, Daniel E, Gerken T, et al.
J Biol Chem . 2020 Jul; 295(35):12525-12536. PMID: 32669364
Mucin-type -glycosylation is an essential post-translational modification required for protein secretion, extracellular matrix formation, and organ growth. -Glycosylation is initiated by a large family of enzymes (GALNTs in mammals and...
5.
Ji S, Samara N, Revoredo L, Zhang L, Tran D, Muirhead K, et al.
Nat Commun . 2018 Aug; 9(1):3508. PMID: 30158631
Regulated secretion is an essential process where molecules destined for export are directed to membranous secretory granules, where they undergo packaging and maturation. Here, we identify a gene (pgant9) that...
6.
Evans D, Venkitachalam S, Revoredo L, Dohey A, Clarke E, Pennell J, et al.
Hum Mutat . 2018 May; 39(8):1092-1101. PMID: 29749045
Characterizing moderate penetrance susceptibility genes is an emerging frontier in colorectal cancer (CRC) research. GALNT12 is a strong candidate CRC-susceptibility gene given previous linkage and association studies, and inactivating somatic...
7.
Festari M, Trajtenberg F, Berois N, Pantano S, Revoredo L, Kong Y, et al.
Glycobiology . 2016 Dec; 27(2):140-153. PMID: 27913570
Polypeptide GalNAc-transferases (GalNAc-Ts) constitute a family of 20 human glycosyltransferases (comprising 9 subfamilies), which initiate mucin-type O-glycosylation. The O-glycoproteome is thought to be differentially regulated via the different substrate specificities...
8.
Venkitachalam S, Revoredo L, Varadan V, Fecteau R, Ravi L, Lutterbaugh J, et al.
Sci Rep . 2016 Mar; 6:23642. PMID: 27004849
The molecular basis of aberrant protein glycosylation, a pathological alteration widespread in colorectal cancers (CRC), and the mechanisms by which it contributes to tumor progression remain largely unknown. We performed...
9.
Revoredo L, Wang S, Bennett E, Clausen H, Moremen K, Jarvis D, et al.
Glycobiology . 2015 Nov; 26(4):360-76. PMID: 26610890
A large family of UDP-GalNAc:polypeptide GalNAc transferases (ppGalNAc-Ts) initiates and defines sites of mucin-type Ser/Thr-O-GalNAc glycosylation. Family members have been classified into peptide- and glycopeptide-preferring subfamilies, although both families possess...
10.
Gerken T, Revoredo L, Thome J, Tabak L, Vester-Christensen M, Clausen H, et al.
J Biol Chem . 2013 May; 288(27):19900-14. PMID: 23689369
Mucin type O-glycosylation is initiated by a large family of polypeptide GalNAc transferases (ppGalNAc Ts) that add α-GalNAc to the Ser and Thr residues of peptides. Of the 20 human...