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Leslie E Norman

Explore the profile of Leslie E Norman including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Nickols N, Mi Z, DeMatt E, Biswas K, Clise C, Huggins J, et al.
JAMA Netw Open . 2022 Apr; 5(4):e227852. PMID: 35438754
Importance: SARS-CoV-2 entry requires the TMPRSS2 cell surface protease. Antiandrogen therapies reduce expression of TMPRSS2. Objective: To determine if temporary androgen suppression induced by degarelix improves clinical outcomes of inpatients...
2.
Nickols N, Goetz M, Graber C, Bhattacharya D, Soo Hoo G, Might M, et al.
Trials . 2021 Jul; 22(1):431. PMID: 34225789
Background: Therapeutic targeting of host-cell factors required for SARS-CoV-2 entry is an alternative strategy to ameliorate COVID-19 severity. SARS-CoV-2 entry into lung epithelium requires the TMPRSS2 cell surface protease. Pre-clinical...