Leslie C Sutherland
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Explore the profile of Leslie C Sutherland including associated specialties, affiliations and a list of published articles.
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26
Citations
482
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Recent Articles
1.
Loiselle J, Knee J, Sutherland L
Data Brief
. 2018 Nov;
21:1568-1572.
PMID: 30480069
Presented herein are RNA expression data linked to the exposure of human lung epithelial cells to either low dose radon-emitting rock, tobacco smoke or cannabis smoke. Two cell lines were...
2.
Loiselle J, Knee J, Sutherland L
J Environ Radioact
. 2018 Nov;
196:64-81.
PMID: 30396064
Radon is the second leading cause of lung cancer, after tobacco smoke. While tobacco smoke-induced carcinogenesis has been studied extensively, far less is known about radon-induced carcinogenesis, particularly in relation...
3.
Regulation of T-Cell Apoptosis by Sequences Encoded at the Luca-15 Candidate Tumour Suppressor Locus
Mourtada-Maarabouni M, Sutherland L, Clark J, Cooper C, Williams G
ScientificWorldJournal
. 2018 Aug;
1:38.
PMID: 30147483
No abstract available.
4.
Loiselle J, Sutherland L
J Cell Biochem
. 2017 Dec;
119(5):3809-3818.
PMID: 29274279
RBM10 is an RNA binding motif (RBM) protein expressed in most, if not all, human and animal cells. Interest in RBM10 is rapidly increasing and its clinical importance is highlighted...
5.
Sutherland L, Thibault P, Durand M, Lapointe E, Knee J, Beauvais A, et al.
BMC Mol Biol
. 2017 Jul;
18(1):19.
PMID: 28728573
Background: RBM10 is an RNA binding protein involved in message stabilization and alternative splicing regulation. The objective of the research described herein was to identify novel targets of RBM10-regulated splicing....
6.
Loiselle J, Roy J, Sutherland L
PLoS One
. 2017 Jun;
12(6):e0180258.
PMID: 28662214
Lung cancers are the leading cause of cancer-related deaths worldwide, with small cell lung cancer (SCLC) being the most aggressive type. At the time of diagnosis, SCLC has usually already...
7.
Loiselle J, Roy J, Sutherland L
Heliyon
. 2016 Dec;
2(11):e00204.
PMID: 27957556
Small cell lung cancer (SCLC) is the most aggressive type of lung cancer, with almost 95% of patients succumbing to the disease. Although , a tumor suppressor gene, is downregulated...
8.
Ozuemba B, Masilamani T, Loiselle J, Koenderink B, Vanderbeck K, Knee J, et al.
Gene
. 2016 Jan;
580(1):26-36.
PMID: 26784654
Background: Expression and function of the two RNA binding proteins and regulators of alternative splicing, RBM5 and RBM10, have largely been studied in human tissue and cell lines. The objective...
9.
Loiselle J, Tessier S, Sutherland L
In Vitro Cell Dev Biol Anim
. 2015 Dec;
52(3):327-336.
PMID: 26659391
We previously examined the expression of Rbm5 during myoblast differentiation and found significantly more protein in the early stages of skeletal myoblast differentiation than during the later stages. We decided...
10.
Wang K, Bacon M, Tessier J, Rintala-Maki N, Tang V, Sutherland L
J Cell Death
. 2015 Oct;
5:1-19.
PMID: 26446321
Recent evidence suggests that protein encoded by the RNA Binding Motif 10 (RBM10) gene has the ability to modulate apoptosis. The objective of this study was to test this hypothesis...