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Leroy R Thacker

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Articles 120
Citations 3945
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Recent Articles
1.
Bajaj J, Fagan A, Gavis E, Sterling R, Gallagher M, Lee H, et al.
J Hepatol . 2025 Jan; PMID: 39800192
Background: Preventing hepatic encephalopathy (HE) recurrence in cirrhosis, which is associated with an altered gut-liver-brain axis, is an unmet need. Fecal microbiota transplantation (FMT) is beneficial in phase-1 studies, but...
2.
Cao Z, Wong F, Choudhury A, Kamath P, Topazian M, Torre A, et al.
Lancet Gastroenterol Hepatol . 2024 Sep; 9(11):997-1009. PMID: 39243795
Background: Infections have a poor prognosis in inpatients with cirrhosis. We aimed to determine regional variations in infections and their association with clinical outcomes in a global cohort of inpatients...
3.
Stouffer J, Bates K, Thacker L, Heatwole C, Johnson N
Neuromuscul Disord . 2024 May; 39:48-53. PMID: 38795602
Limb girdle muscular dystrophy (LGMD) is a debilitating disease and the fourth most common muscular dystrophy. This study describes the development of the LGMD-Health Index (LGMD-HI). Participants were aged >18...
4.
Poklepovic A, Gordon S, Kothadia S, McGuire W, Thacker L, Deng X, et al.
Anticancer Drugs . 2024 Mar; 35(5):450-458. PMID: 38452059
The purpose of this study is to establish the recommended phase 2 dose for regorafenib in combination with sildenafil for patients with advanced solid tumors. Secondary outcomes included identification of...
5.
Sloss E, Jones T, Baker K, Robins J, Thacker L
Comput Inform Nurs . 2024 Jan; 42(3):199-206. PMID: 38206171
Paramount to patient safety is the ability for nurses to make clinical decisions free from human error. Yet, the dynamic clinical environment in which nurses work is characterized by uncertainty,...
6.
Sloss E, Jones T, Baker K, Robins J, Thacker L
Comput Inform Nurs . 2023 Dec; 42(2):94-103. PMID: 38062552
The aim of this study was to describe medication administration and alert patterns among a cohort of new graduate nurses over the first year of practice. Medical errors related to...
7.
Bajaj J, Kamath P, Reddy K, Asrani S, Keaveny A, Tandon P, et al.
Am J Gastroenterol . 2023 Nov; 119(4):712-718. PMID: 37938163
Introduction: Hospitalized patients with cirrhosis can develop respiratory failure (RF), which is associated with a poor prognosis, but predisposing factors are unclear. Methods: We prospectively enrolled a multicenter North American...
8.
Sargent L, Zimmerman K, Mohammed A, Barrett M, Nawaz H, Wyman-Chick K, et al.
Drugs Aging . 2023 Oct; 40(12):1123-1131. PMID: 37856064
Background: A growing body of research supports the negative impact of anticholinergic drug burden on physical frailty. However, prior research has been limited to homogeneous white European populations, and few...
9.
Kanagalingam G, Park D, Badal B, Fagan A, Thacker L, Bajaj J
Clin Gastroenterol Hepatol . 2023 Oct; 22(4):899-901.e2. PMID: 37797903
Cirrhosis-related neurocognitive impairment caused by covert or minimal hepatic encephalopathy (CHE) affects psychosocial function, increases risk of overt hepatic encephalopathy (OHE) development, and worsens survival. However, detection in clinical practice...
10.
Kinser P, Bodnar-Deren S, Amstadter A, Lapato D, Thacker L, Johnson J, et al.
Contemp Clin Trials . 2023 Jul; 132:107302. PMID: 37500008
More than 1 in 5 pregnant people in the United States experience depressive symptoms. Although treatments exist, many people remain under- or un-treated due to concerns about stigma, side effects,...