Leroy E Hood
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Explore the profile of Leroy E Hood including associated specialties, affiliations and a list of published articles.
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29
Citations
2081
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Recent Articles
1.
Yurkovich J, Evans S, Rappaport N, Boore J, Lovejoy J, Price N, et al.
Nat Rev Genet
. 2023 Dec;
25(4):286-302.
PMID: 38093095
Modern health care faces several serious challenges, including an ageing population and its inherent burden of chronic diseases, rising costs and marginal quality metrics. By assessing and optimizing the health...
2.
Jabbari N, Kenerson H, Lausted C, Yan X, Meng C, Sullivan K, et al.
Cell Rep Med
. 2020 Dec;
1(9):100160.
PMID: 33377131
Metastatic colorectal cancer (CRC) is a major cause of cancer-related death, and incidence is rising in younger populations (younger than 50 years). Current chemotherapies can achieve response rates above 50%,...
3.
Trachana K, Bargaje R, Glusman G, Price N, Huang S, Hood L
Circ Res
. 2018 Apr;
122(9):1276-1289.
PMID: 29700072
Systems medicine is a holistic approach to deciphering the complexity of human physiology in health and disease. In essence, a living body is constituted of networks of dynamically interacting units...
4.
Ament S, Pearl J, Cantle J, Bragg R, Skene P, Coffey S, et al.
Mol Syst Biol
. 2018 Mar;
14(3):e7435.
PMID: 29581148
Transcriptional changes occur presymptomatically and throughout Huntington's disease (HD), motivating the study of transcriptional regulatory networks (TRNs) in HD We reconstructed a genome-scale model for the target genes of 718...
5.
Hood L
Genomics Proteomics Bioinformatics
. 2018 Mar;
16(1):1-9.
PMID: 29496591
No abstract available.
6.
Meng C, Bai C, Brown T, Hood L, Tian Q
Genomics Proteomics Bioinformatics
. 2018 Feb;
16(1):33-49.
PMID: 29474889
Human gut microbiota play an essential role in both healthy and diseased states of humans. In the past decade, the interactions between microorganisms and tumors have attracted much attention in...
7.
Bennett J, Hood L, Dreyer W, Potter M
J Immunol
. 2017 Dec;
200(1):27-37.
PMID: 29255087
No abstract available.
8.
Glusman G, Mauldin D, Hood L, Robinson M
Front Genet
. 2017 Oct;
8:136.
PMID: 29018478
We present an ultrafast method for comparing personal genomes. We transform the standard genome representation (lists of variants relative to a reference) into "genome fingerprints" via locality sensitive hashing. The...
9.
Wei K, Chen C, Feng L, Huang W, Chen C, Hsu P, et al.
PLoS One
. 2017 Jun;
12(6):e0178842.
PMID: 28575062
The methylation status of O-6-methylguanine-DNA methyltransferase (MGMT) is associated with the prognosis in gliomas and in other cancers. Recent studies showed that rs16906252, an SNP in the MGMT promoter, is...
10.
Ament S, Pearl J, Grindeland A, St Claire J, Earls J, Kovalenko M, et al.
Hum Mol Genet
. 2017 Mar;
26(5):913-922.
PMID: 28334820
Huntington's disease is a dominantly inherited neurodegenerative disease caused by the expansion of a CAG repeat in the HTT gene. In addition to the length of the CAG expansion, factors...