Leonor C Acosta-Saavedra
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Explore the profile of Leonor C Acosta-Saavedra including associated specialties, affiliations and a list of published articles.
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13
Citations
164
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Recent Articles
1.
Ocharan-Mercado A, Loaeza-Loaeza J, Castro-Coronel Y, Acosta-Saavedra L, Hernandez-Kelly L, Hernandez-Sotelo D, et al.
Neurotox Res
. 2023 Sep;
41(6):681-697.
PMID: 37776476
Despite sustained efforts to treat neurodegenerative diseases, little is known at the molecular level to understand and generate novel therapeutic approaches for these malignancies. Therefore, it is not surprising that...
2.
Martinez-Hernandez M, Acosta-Saavedra L, Hernandez-Kelly L, Loaeza-Loaeza J, Ortega A
Biomed Res Int
. 2023 Feb;
2023:7389508.
PMID: 36760476
Neurodegenerative processes encompass a large variety of diseases with different pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases. Exposure to metals has been hypothesized to increase oxidative...
3.
Albores-Garcia D, Acosta-Saavedra L, Hernandez A, Loera M, Calderon-Aranda E
Biomed Res Int
. 2016 Feb;
2016:6532108.
PMID: 26885512
Few studies have assessed the effects of developmental methylmercury (MeHg) exposure on learning and memory at different ages. The possibility of the amelioration or worsening of the effects has not...
4.
Meraz-Rios M, Majluf-Cruz A, Santana C, Noris G, Camacho-Mejorado R, Acosta-Saavedra L, et al.
Biomed Res Int
. 2014 Sep;
2014:697689.
PMID: 25250329
Objective: Venous thromboembolism (VTE) is a multifactorial disorder and, worldwide, the most important cause of morbidity and mortality. Genetic factors play a critical role in its aetiology. Microsatellites are the...
5.
Luna A, Acosta-Saavedra L, Martinez M, Torres-Aviles N, Gomez R, Calderon-Aranda E
Toxicol Lett
. 2012 Sep;
214(3):301-6.
PMID: 23000830
Lead (Pb) alters the susceptibility to different pathogens suggesting that macrophage-mediated defense mechanisms, through activation of toll-like receptors (TLRs), may be affected by Pb. The aim of this study was...
6.
Acosta-Saavedra L, Moreno M, Rodriguez-Kessler T, Luna A, Arias-Salvatierra D, Gomez R, et al.
Toxicol Mech Methods
. 2011 Oct;
21(9):656-66.
PMID: 21981766
Exposure to lead (Pb) and mercury (Hg) remains a world public health problem, particularly for young children in developing countries. In Mexico, the main sources of exposure to Pb and...
7.
Arias-Salvatierra D, Silbergeld E, Acosta-Saavedra L, Calderon-Aranda E
Cell Signal
. 2010 Oct;
23(2):425-35.
PMID: 20955790
Inflammatory stimulus during development increases the risk for adverse neurologic outcome. One possible mechanism is disrupting neuronal migration. Using lipopolysaccharide (LPS)-treatment to assess inflammatory stimulus on neuronal migration of cerebellar...
8.
Moreno M, Acosta-Saavedra L, Meza-Figueroa D, Vera E, Cebrian M, Ostrosky-Wegman P, et al.
Int J Hyg Environ Health
. 2010 Apr;
213(4):252-8.
PMID: 20418157
Accumulation of metals in soil represents a health risk for individuals living near mining areas, especially for children who have a higher susceptibility to metal related diseases. The Taxco mining...
9.
Luna A, Acosta-Saavedra L, Lopez-Carrillo L, Conde P, Vera E, De Vizcaya-Ruiz A, et al.
Toxicol Appl Pharmacol
. 2010 Mar;
245(2):244-51.
PMID: 20226805
Arsenic (As) exposure has been associated with alterations in the immune system, studies in experimental models and adults have shown that these effects involve macrophage function; however, limited information is...
10.
Conde P, Acosta-Saavedra L, Goytia-Acevedo R, Calderon-Aranda E
Arch Toxicol
. 2006 Sep;
81(4):251-9.
PMID: 17009048
A proposed mechanism for the As-induced inhibition of cell proliferation is the inhibition of IL-2 secretion. However, the effects of arsenite on IL-2 mRNA expression or on the ERK pathway...