Leonilde M Moreira
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Explore the profile of Leonilde M Moreira including associated specialties, affiliations and a list of published articles.
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35
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1093
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Recent Articles
1.
Seixas A, Gomes S, Silva C, Moreira L, Leitao J, Sousa S
Vaccines (Basel)
. 2024 Feb;
12(2).
PMID: 38400190
Despite advances in therapies, bacterial chronic respiratory infections persist as life-threatening to patients suffering from cystic fibrosis (CF). and bacteria of the complex are among the most difficult of these...
2.
Ferreira M, Queiroga V, Moreira L
Appl Environ Microbiol
. 2024 Feb;
90(2):e0225023.
PMID: 38299816
complex bacteria have emerged as opportunistic pathogens in patients with cystic fibrosis and immunocompromised individuals, causing life-threatening infections. Because of the relevance of these microorganisms, genetic manipulation is crucial for...
3.
Seixas A, Sousa S, Feliciano J, Gomes S, Ferreira M, Moreira L, et al.
Biomedicines
. 2021 Dec;
9(12).
PMID: 34944603
Respiratory infections by bacteria of the complex (Bcc) remain a life threat to cystic fibrosis (CF) patients, due to the faster lung function decline and the absence of effective eradication...
4.
Gomes S, Ferreira M, Tavares A, Silva I, Becker J, Moreira L
Appl Environ Microbiol
. 2021 May;
87(14):e0036921.
PMID: 33931418
Burkholderia cepacia complex bacteria comprise opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. These microorganisms produce an exopolysaccharide named cepacian, which is considered a virulence determinant. To...
5.
Silva T, Sousa-Luis R, Fernandes T, Bekman E, Rodrigues C, Vaz S, et al.
Biotechnol Bioeng
. 2021 Apr;
118(7):2781-2803.
PMID: 33871054
Human-induced pluripotent stem cells (iPSCs) have great potential for disease modeling. However, generating iPSC-derived models to study brain diseases remains a challenge. In particular, the ability to recapitulate cerebellar development...
6.
A Branco M, Cotovio J, Rodrigues C, Vaz S, Fernandes T, Moreira L, et al.
Sci Rep
. 2019 Jun;
9(1):9229.
PMID: 31239450
Human induced pluripotent stem cells (hiPSCs) represent an almost limitless source of cells for disease modelling and drug screening applications. Here we established an efficient and robust 3D platform for...
7.
Ferreira M, Gomes S, Moreira L
Adv Appl Microbiol
. 2019 May;
107:113-140.
PMID: 31128746
Bacteria produce a vast range of exopolysaccharides (EPSs) to thrive in diverse environmental niches and often display a mucoid phenotype in solid media. One such exopolysaccharide, cepacian, is produced by...
8.
Silva I, Pessoa F, Ramires M, Santos M, Becker J, Cooper V, et al.
J Bacteriol
. 2018 Jun;
200(17).
PMID: 29914989
Bacteria from the complex grow in different natural and man-made environments and are feared opportunistic pathogens that cause chronic respiratory infections in cystic fibrosis patients. Previous studies showed that mucoid...
9.
Sousa P, Silva I, Moreira L, Verissimo A, Costa J
Front Cell Infect Microbiol
. 2018 Apr;
8:97.
PMID: 29670859
is a ubiquitous bacterium in freshwater environments and in many man-made water systems capable of inducing pneumonia in humans. Despite its ubiquitous character most studies on virulence focused on clinical...
10.
Silva I, Ramires M, Azevedo L, Guerreiro A, Tavares A, Becker J, et al.
Appl Environ Microbiol
. 2017 Jul;
83(19).
PMID: 28733286
LysR-type transcriptional regulators (LTTRs) are the most commonly found regulators in complex, comprising opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. Despite LTTRs being global regulators of...