Leonie van Stuijvenberg
Overview
Explore the profile of Leonie van Stuijvenberg including associated specialties, affiliations and a list of published articles.
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14
Citations
318
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Recent Articles
1.
Kessler E, Wang J, Kok B, Brans M, Nederlof A, van Stuijvenberg L, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769252
Involvement of the Toll-like receptor 4 (TLR4) in maladaptive cardiac remodeling and heart failure (HF) upon pressure overload has been studied extensively, but less is known about the role of...
2.
Driessen H, Fontes M, van Stuijvenberg L, Brans M, Goumans M, Vos M, et al.
J Cell Mol Med
. 2020 Jun;
24(15):8417-8429.
PMID: 32573944
In the diseased and remodelled heart, increased activity and expression of Ca calmodulin-dependent protein kinase II (CaMKII), an excess of fibrosis, and a decreased electrical coupling and cellular excitability leads...
3.
Kessler E, van Stuijvenberg L, Van Bavel J, van Bennekom J, Zwartsen A, Rivaud M, et al.
J Mol Cell Cardiol
. 2018 Nov;
126:86-95.
PMID: 30452906
Background: The intercalated disc (ID) is important for cardiac remodeling and has become a subject of intensive research efforts. However, as yet the composition of the ID has still not...
4.
Takanari H, Bourgonje V, Fontes M, Raaijmakers A, Driessen H, Jansen J, et al.
Cardiovasc Res
. 2016 Jul;
111(4):410-21.
PMID: 27357638
Aim: In healthy hearts, ventricular gap junctions are mainly composed by connexin43 (Cx43) and localize in the intercalated disc, enabling appropriate electrical coupling. In diseased hearts, Cx43 is heterogeneously down-regulated,...
5.
Soni S, Raaijmakers A, Raaijmakers L, Damen J, van Stuijvenberg L, Vos M, et al.
PLoS One
. 2016 May;
11(5):e0152231.
PMID: 27148881
Aims: Synchronous beating of the heart is dependent on the efficient functioning of the cardiac intercalated disk (ID). The ID is composed of a complex protein network enabling electrical continuity...
6.
Fontes M, Kessler E, van Stuijvenberg L, Brans M, Falke L, Kok B, et al.
J Mol Cell Cardiol
. 2015 Sep;
88:82-90.
PMID: 26410398
Background: One of the main contributors to maladaptive cardiac remodeling is fibrosis. Connective tissue growth factor (CTGF), a matricellular protein that is secreted into the cardiac extracellular matrix by both...
7.
Vreeker A, van Stuijvenberg L, Hund T, Mohler P, Nikkels P, van Veen T
PLoS One
. 2014 Apr;
9(4):e94722.
PMID: 24733085
Background: In cardiac muscle, the intercalated disk (ID) at the longitudinal cell-edges of cardiomyocytes provides as a macromolecular infrastructure that integrates mechanical and electrical coupling within the heart. Pathophysiological disturbance...
8.
Noorman M, Hakim S, Kessler E, Groeneweg J, Cox M, Asimaki A, et al.
Heart Rhythm
. 2012 Nov;
10(3):412-9.
PMID: 23178689
Background: Arrhythmogenic cardiomyopathy (AC) is closely associated with desmosomal mutations in a majority of patients. Arrhythmogenesis in patients with AC is likely related to remodeling of cardiac gap junctions and...
9.
Noorman M, Groeneweg J, Asimaki A, Rizzo S, Papegaaij M, van Stuijvenberg L, et al.
Heart Rhythm
. 2012 Oct;
10(2):283-9.
PMID: 23085127
Detailed histopathologic, immunohistochemical, and ultrastructural analysis of the heart of a 56-year-old woman with end-stage arrhythmogenic cardiomyopathy with a pathogenic plakophilin-2 mutation is described. The explanted heart revealed severe fibrofatty...
10.
Chaldoupi S, Hubens L, Smit Duijzentkunst D, van Stuijvenberg L, Bierhuizen M, van Aarnhem E, et al.
Europace
. 2012 Mar;
14(8):1199-205.
PMID: 22423256
Aims: The occurrence of connexin40 (Cx40) minor polymorphism (-44 G → A) was increased in patients with idiopathic atrial fibrillation (AF), although its effect on atrial Cx40 protein expression is...