Leon Di Stefano
Overview
Explore the profile of Leon Di Stefano including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
528
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Recent Articles
1.
Brantner C, Chang T, Nguyen T, Hong H, Stefano L, Stuart E
Stat Sci
. 2024 Apr;
38(4):640-654.
PMID: 38638306
Estimating treatment effects conditional on observed covariates can improve the ability to tailor treatments to particular individuals. Doing so effectively requires dealing with potential confounding, and also enough data to...
2.
Stefano L, Ram M, Scharfstein D, Li T, Khanal P, Baksh S, et al.
Medicine (Baltimore)
. 2023 Jun;
102(23):e33904.
PMID: 37335665
Background: Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers (ARBs) have been hypothesized to benefit patients with COVID-19 via the inhibition of viral entry and other mechanisms. We conducted an...
3.
Stefano L, Ogburn E, Ram M, Scharfstein D, Li T, Khanal P, et al.
PLoS One
. 2022 Sep;
17(9):e0273526.
PMID: 36173983
Background: Results from observational studies and randomized clinical trials (RCTs) have led to the consensus that hydroxychloroquine (HCQ) and chloroquine (CQ) are not effective for COVID-19 prevention or treatment. Pooling...
4.
Stefano L, Ogburn E, Ram M, Scharfstein D, Li T, Khanal P, et al.
medRxiv
. 2022 Jan;
PMID: 35043124
Background: Results from observational studies and randomized clinical trials (RCTs) have led to the consensus that hydroxychloroquine (HCQ) and chloroquine (CQ) are not effective for COVID-19 prevention or treatment. Pooling...
5.
Pal B, Chen Y, Vaillant F, Capaldo B, Joyce R, Song X, et al.
EMBO J
. 2021 May;
40(11):e107333.
PMID: 33950524
To examine global changes in breast heterogeneity across different states, we determined the single-cell transcriptomes of > 340,000 cells encompassing normal breast, preneoplastic BRCA1 tissue, the major breast cancer subtypes,...
6.
Bedo J, Stefano L, Papenfuss A
Gigascience
. 2020 Nov;
9(11).
PMID: 33205815
Motivation: A challenge for computational biologists is to make our analyses reproducible-i.e. to rerun, combine, and share, with the assurance that equivalent runs will generate identical results. Current best practice...
7.
Cameron D, Stefano L, Papenfuss A
Nat Commun
. 2019 Jul;
10(1):3240.
PMID: 31324872
In recent years, many software packages for identifying structural variants (SVs) using whole-genome sequencing data have been released. When published, a new method is commonly compared with those already available,...
8.
Janic A, Valente L, Wakefield M, Stefano L, Milla L, Wilcox S, et al.
Nat Med
. 2018 Jun;
24(7):947-953.
PMID: 29892060
It has long been assumed that p53 suppresses tumor development through induction of apoptosis, possibly with contributions by cell cycle arrest and cell senescence. However, combined deficiency in these three...
9.
Adema C, Hillier L, Jones C, Loker E, Knight M, Minx P, et al.
Nat Commun
. 2017 Aug;
8:16153.
PMID: 28832025
This corrects the article DOI: 10.1038/ncomms15451.
10.
Colebatch A, Stefano L, Wong S, Hannan R, Waring P, Dobrovic A, et al.
Oncotarget
. 2016 Sep;
7(41):66569-66585.
PMID: 27611953
Most cancer DNA sequencing studies have prioritized recurrent non-synonymous coding mutations in order to identify novel cancer-related mutations. Although attention is increasingly being paid to mutations in non-coding regions, standard...