Leo A M Aerden
Overview
Explore the profile of Leo A M Aerden including associated specialties, affiliations and a list of published articles.
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13
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2401
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Recent Articles
1.
Zonneveld T, Vermeer S, van Zwet E, Groot A, Algra A, Aerden L, et al.
Lancet Neurol
. 2024 May;
23(8):807-815.
PMID: 38763149
Background: Intravenous thrombolysis is contraindicated in patients with ischaemic stroke with blood pressure higher than 185/110 mm Hg. Prevailing guidelines recommend to actively lower blood pressure with intravenous antihypertensive agents...
2.
Roelofs J, Zandvliet S, Schut I, Huisinga A, Schouten A, Hendricks H, et al.
Neurorehabil Neural Repair
. 2023 Oct;
37(11-12):786-798.
PMID: 37877724
Background: After mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels. To investigate whether individuals in the chronic phase...
3.
Dekker L, Daems J, Duvekot M, Nguyen T, Venema E, van Es A, et al.
Stroke
. 2023 Jul;
54(9):2279-2285.
PMID: 37465998
Background: It is unknown if ambulance paramedics adequately assess neurological deficits used for prehospital stroke scales to detect anterior large-vessel occlusions. We aimed to compare prehospital assessment of these stroke-related...
4.
Duvekot M, Garcia B, Dekker L, Nguyen T, van den Wijngaard I, de Laat K, et al.
Prehosp Emerg Care
. 2023 May;
27(5):630-638.
PMID: 37219931
Background And Purpose: Direct transportation to a thrombectomy-capable intervention center is beneficial for patients with ischemic stroke due to large vessel occlusion (LVO), but can delay intravenous thrombolytics (IVT). The...
5.
van der Ende N, Roozenbeek B, Smagge L, Luijten S, Aerden L, Kraayeveld P, et al.
JAMA Neurol
. 2023 May;
80(7):714-722.
PMID: 37213122
Importance: Dual thrombolytic treatment with small bolus alteplase and mutant prourokinase has the potential to be a safer and more efficacious treatment for ischemic stroke than alteplase alone because mutant...
6.
van der Ende N, Roozenbeek B, Smagge L, Luijten S, Aerden L, Kraayeveld P, et al.
Trials
. 2022 Aug;
23(1):641.
PMID: 35945566
Background: The effectiveness of alteplase for ischemic stroke treatment is limited, partly due to the occurrence of intracranial and extracranial hemorrhage. Mutant pro-urokinase (m-proUK) does not deplete fibrinogen and lyses...
7.
van der Velde M, Aerden L, van Oort A, Bodde K, Rambaran Mishre R, Oosterveer D
Neuropsychol Rehabil
. 2022 Jan;
33(3):428-439.
PMID: 35019819
Anxiety and depression are common mental health disorders in stroke patients, and often co-occur. However, in contrast to depression, there is limited research about anxiety after stroke, although impact of...
8.
van Kordelaar J, van de Ruit M, Solis-Escalante T, Aerden L, Meskers C, van Wegen E, et al.
Front Hum Neurosci
. 2021 Dec;
15:695366.
PMID: 34858150
Proprioception is important for regaining motor function in the paretic upper extremity after stroke. However, clinical assessments of proprioception are subjective and require verbal responses from the patient to applied...
9.
Nguyen T, van den Wijngaard I, Bosch J, van Belle E, van Zwet E, Dofferhoff-Vermeulen T, et al.
JAMA Neurol
. 2020 Nov;
78(2):157-164.
PMID: 33252631
Importance: The efficacy of endovascular thrombectomy (EVT) for symptomatic large anterior vessel occlusion (sLAVO) sharply decreases with time. Because EVT is restricted to comprehensive stroke centers, prehospital triage of patients...
10.
Oosterveer D, Rambaran Mishre R, van Oort A, Bodde K, Aerden L
J Rehabil Med
. 2017 Feb;
49(3):223-227.
PMID: 28218342
Objective: Life satisfaction is reduced in stroke patients. However, as a rule, rehabilitation goals are not aimed at life satisfaction, but at activities and participation. In order to optimize life...