Lena Norberg-Spaak
Overview
Explore the profile of Lena Norberg-Spaak including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
108
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0
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Recent Articles
1.
Salehi A, Norberg-Spaak L, Wilms T, Vallin S, Boldrup L, Sgaramella N, et al.
Case Rep Oncol
. 2020 Nov;
13(3):1295-1303.
PMID: 33250745
Studies have shown lower treatment-related morbidity when using transoral robotic surgery (TORS) compared to conventional surgery. Patients investigated for oro- and hypopharyngeal cancer (T1, T2) were compared concerning quality of...
2.
Salehi A, Norberg-Spaak L, Vallin S, Sgaramella N, Nylander K
Oncology
. 2020 Sep;
98(12):889-892.
PMID: 32882692
Introduction: To compare data from preoperative positron emission tomography/computed tomography (PET/CT) with results of panscopy with biopsy and ultrasound with fine needle aspiration cytology (US-FNAC) on the same patients. Methods:...
3.
Boldrup L, Coates P, Gu X, Wang L, Fahraeus R, Wilms T, et al.
Oncol Lett
. 2020 Jul;
20(2):1709-1718.
PMID: 32724413
Mucin 1 (MUC1) is a membrane-bound and secreted glycoprotein that has a protective role in surface epithelia. We recently demonstrated that MUC1 mRNA expression was upregulated in tumour-free tongue tissues...
4.
PD-L1 in squamous cell carcinoma of the oral tongue shows gender-specific association with prognosis
Wilms T, Gu X, Boldrup L, Coates P, Fahraeus R, Wang L, et al.
Oral Dis
. 2020 May;
26(7):1414-1423.
PMID: 32406589
Objective: To use alternative quantitation approaches to clarify the clinical implication of programmed cell death ligand 1 (PD-L1) in squamous cell carcinoma of the oral tongue (SCCOT). Materials And Methods:...
5.
Gu X, Boldrup L, Coates P, Fahraeus R, Wang L, Wilms T, et al.
J Pathol Clin Res
. 2019 Jun;
5(4):240-247.
PMID: 31237113
Immune cells and cytolytic activity within the tumor microenvironment are being intensively studied. Through transcriptome profiling, immune cell enumeration using the xCell tool and cytolytic activity quantification according to granzyme...
6.
Gu X, Coates P, Boldrup L, Wang L, Krejci A, Hupp T, et al.
J Oral Pathol Med
. 2018 Oct;
48(1):24-30.
PMID: 30357923
Background: The incidence of squamous cell carcinoma of the oral tongue (SCCOT) is increasing in people under age 40. There is an urgent need to identify prognostic markers that help...
7.
Boldrup L, Troiano G, Gu X, Coates P, Fahraeus R, Wilms T, et al.
Oncotarget
. 2017 Dec;
8(61):103437-103448.
PMID: 29262574
Despite intense research, squamous cell carcinoma of the tongue remains a devastating disease with a five-year survival of around 60%. Late detection and recurrence are the main causes for poor...
8.
Strindlund K, Troiano G, Sgaramella N, Coates P, Gu X, Boldrup L, et al.
J Oral Pathol Med
. 2017 Apr;
46(10):967-971.
PMID: 28393404
Background: c-MYC is a potent oncoprotein with roles in a wide range of cellular processes such as differentiation, apoptosis and growth control. Deregulation of the MYC gene is commonly seen...
9.
Boldrup L, Gu X, Coates P, Norberg-Spaak L, Fahraeus R, Laurell G, et al.
Oncotarget
. 2016 Dec;
8(12):19389-19402.
PMID: 28038473
Due to the high frequency of loco-regional recurrences, which could be explained by changes in the field surrounding the tumor, patients with squamous cell carcinoma of head and neck show...
10.
Gu X, Boldrup L, Coates P, Fahraeus R, Nylander E, Loizou C, et al.
Sci Rep
. 2016 Aug;
6:32579.
PMID: 27572959
Epigenetic modifications are essential regulators of biological processes. Decreased DNA methylation of OAS2 (2'-5'-Oligoadenylate Synthetase 2), encoding an antiviral protein, has been seen in psoriasis. To provide further insight into...