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Lena Neufeld

Explore the profile of Lena Neufeld including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 168
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Recent Articles
1.
Madan E, Palma A, Vudatha V, Kumar A, Bhoopathi P, Wilhelm J, et al.
Nat Biotechnol . 2024 Dec; PMID: 39653752
Cell competition and fitness comparison between cancer and tumor microenvironment (TME) cells determine oncogenic fate. Our previous study established a role for human Flower isoforms as fitness fingerprints, where the...
2.
Neufeld L, Yeini E, Pozzi S, Satchi-Fainaro R
Nat Rev Cancer . 2022 Oct; 22(12):679-692. PMID: 36280768
Effort invested in the development of new drugs often fails to be translated into meaningful clinical benefits for patients with cancer. The development of more effective anticancer therapeutics and accurate...
3.
Neufeld L, Yeini E, Reisman N, Shtilerman Y, Ben-Shushan D, Pozzi S, et al.
Sci Adv . 2021 Aug; 7(34). PMID: 34407932
Many drugs show promising results in laboratory research but eventually fail clinical trials. We hypothesize that one main reason for this translational gap is that current cancer models are inadequate....
4.
Pozzi S, Scomparin A, Israeli Dangoor S, Ajamil D, Ofek P, Neufeld L, et al.
Adv Drug Deliv Rev . 2021 Apr; 175:113760. PMID: 33838208
The complexity and diversity of the biochemical processes that occur during tumorigenesis and metastasis are frequently over-simplified in the traditional in vitro cell cultures. Two-dimensional cultures limit researchers' experimental observations...
5.
Neufeld L, Bianco-Peled H
Int J Biol Macromol . 2017 Apr; 101:852-861. PMID: 28366853
Pectin-chitosan hydrogels are intriguing and relatively new type of physically crosslinked hydrogels. Here we present for the first time a study exploring the suitability of pectin-chitosan hydrogels to serve as...
6.
Neufeld L, Bianco-Peled H
Int J Pharm . 2015 Jun; 491(1-2):170-9. PMID: 26116013
A new design for nanocomposite hydrogels based on cross-linked chitosan for the delivery of mesalamine is presented. To enhance drug loading in chitosan, the mineral montmorillonite was incorporated into the...
7.
Yom-Tov O, Neufeld L, Seliktar D, Bianco-Peled H
Acta Biomater . 2014 Jul; 10(10):4236-46. PMID: 25034645
The use of injectable porous hydrogels is of great interest in biomedical applications due to their excellent permeability and ease of integration into sites of surgical intervention. By implementing a...