Leisa Lopes-Aguiar
Overview
Explore the profile of Leisa Lopes-Aguiar including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
130
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Recent Articles
1.
Angelo da Silva Miyaguti N, de Matuoka E Chiocchetti G, De Moraes Salgado C, Lopes-Aguiar L, Viana L, Blanchard L, et al.
Metabolites
. 2021 Dec;
11(12).
PMID: 34940589
Cancer cachexia occurs in up to 85% of advanced cancer patients, affecting different tissues and organs, mainly the liver, which plays a central role in body metabolism control. However, liver...
2.
de Matuoka E Chiocchetti G, Lopes-Aguiar L, Angelo da Silva Miyaguti N, Viana L, De Moraes Salgado C, Orvoen O, et al.
Metabolites
. 2021 Jul;
11(6).
PMID: 34202988
Cancer cachexia is a severe wasting condition that needs further study to find ways to minimise the effects of damage and poor prognosis. Skeletal muscle is the most impacted tissue...
3.
Ferracini A, Lopes-Aguiar L, Lourenco G, Yoshida A, Lima C, Sarian L, et al.
Clin Transl Sci
. 2020 Dec;
14(2):720-728.
PMID: 33326171
Variation in drug disposition genes might contribute to susceptibility to toxicities and interindividual differences in clinical management on chemotherapy for epithelial ovarian cancer (EOC). This study was designed to explore...
4.
Carvalho B, Dias Costa E, Lopes-Aguiar L, Liutti V, Leal F, Vasconcelos V, et al.
J Oral Pathol Med
. 2020 Aug;
49(10):1078-1083.
PMID: 32816327
Background: Abnormalities in the intrinsic apoptosis pathway, associated with single nucleotide variants (SNVs) in caspase (CASP) genes, alter head and neck squamous cell carcinoma (HNSCC) proliferation and progression. This prospective...
5.
Cruz B, Oliveira A, Viana L, Lopes-Aguiar L, Canevarolo R, Colombera M, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32668598
Cancer-cachexia induces a variety of metabolic disorders, including skeletal muscle imbalance. Alternative therapy, as nutritional supplementation with leucine, shows a modulatory effect over tumour damage in vivo and in vitro....
6.
Dias Costa E, Lima T, Lopes-Aguiar L, Nogueira G, Visacri M, Quintanilha J, et al.
Tumour Biol
. 2020 Jul;
42(7):1010428320938494.
PMID: 32628088
Radiotherapy and cisplatin lead to cell killing in head and neck squamous cell carcinoma patients, but adverse events and response to treatment are not the same in patients with similar...
7.
Viana L, Lopes-Aguiar L, Rosolen R, Santos R, Gomes-Marcondes M
Metabolites
. 2020 Apr;
10(4).
PMID: 32326296
Sarcopenia among the older population has been growing over the last few years. In addition, the incidence of cancers increases with age and, consequently, the development of cachexia related cancer....
8.
Tortorelli G, Torricelli C, Carron J, Dias Costa E, Lopes-Aguiar L, Carvalho B, et al.
Mol Biol Rep
. 2019 Oct;
46(6):6557-6563.
PMID: 31587185
The objective of this research was to assess the association of genetic polymorphisms related to intrinsic apoptosis pathway CASP8 rs3834129 and CASP3 rs4647601 with the risk, clinical and pathological aspects,...
9.
Pincinato E, Costa E, Lopes-Aguiar L, Nogueira G, Lima T, Visacri M, et al.
Sci Rep
. 2019 Jun;
9(1):9312.
PMID: 31249357
Cisplatin (CDDP) combined with radiotherapy (RT) is employed in head and neck squamous cell carcinoma (HNSCC) with variable toxicities and clinical response. Glutathione S-transferases (GSTs) participate in CDDP excretion from...
10.
Dias Costa E, Lopes-Aguiar L, Nogueira G, Lima T, Rinck-Junior J, Lourenco G, et al.
Head Neck
. 2019 Mar;
41(8):2665-2670.
PMID: 30903678
Background: Single nucleotide polymorphisms (SNPs) in genes that act in intrinsic apoptosis pathway may modulate cancer susceptibility. This study investigated the roles of CASP9 c.-1339A>G (rs4645978) and CASP3 c.-1191A>G (rs12108497)...