Leila N Varghese
Overview
Explore the profile of Leila N Varghese including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
1458
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Andrew E, Lewin J, Desai J, Orme L, Hamilton A, Bae S, et al.
J Pers Med
. 2024 Feb;
14(2).
PMID: 38392562
Sarcomas are a heterogenous group of tumours that commonly carry poor prognosis with limited therapeutic options. Adolescents and young adults (AYAs) with sarcoma are a unique and understudied patient population...
2.
Varghese L, Carreno-Tarragona G, Levy G, Gutierrez-Lopez de Ocariz X, Rapado I, Martinez-Lopez J, et al.
Blood Cancer J
. 2021 Nov;
11(11):188.
PMID: 34845187
No abstract available.
3.
Basso-Valentina F, Levy G, Varghese L, Oufadem M, Neven B, Boussard C, et al.
Blood
. 2021 May;
138(6):480-485.
PMID: 34010413
Congenital amegakaryocytic thrombocytopenia (CAMT) is a severe inherited thrombocytopenia due to loss-of-function mutations affecting the thrombopoietin (TPO) receptor, MPL. Here, we report a new homozygous MPL variant responsible for CAMT...
4.
Carreno-Tarragona G, Varghese L, Sebastian E, Galvez E, Marin-Sanchez A, Lopez-Munoz N, et al.
Leukemia
. 2021 Apr;
35(11):3295-3298.
PMID: 33846542
No abstract available.
5.
Levy G, Carillo S, Papoular B, Cassinat B, Zini J, Leroy E, et al.
Blood
. 2020 Jan;
135(12):948-953.
PMID: 31978223
Mutations in the MPL gene encoding the human thrombopoietin receptor (TpoR) drive sporadic and familial essential thrombocythemias (ETs). We identified 2 ET patients harboring double mutations in cis in MPL,...
6.
Constantinescu S, Varghese L
Blood
. 2020 Jan;
135(4):236-237.
PMID: 31972012
No abstract available.
7.
Vainchenker W, Plo I, Marty C, Varghese L, Constantinescu S
Expert Rev Hematol
. 2019 May;
12(6):437-448.
PMID: 31092065
: Classical Myeloproliferative Neoplasms (MPNs) include three disorders: Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF). MPNs are associated with constitutive activation of JAK2 leading to persistent cell...
8.
Varghese L, Defour J, Pecquet C, Constantinescu S
Front Endocrinol (Lausanne)
. 2017 Apr;
8:59.
PMID: 28408900
A well-functioning hematopoietic system requires a certain robustness and flexibility to maintain appropriate quantities of functional mature blood cells, such as red blood cells and platelets. This review focuses on...
9.
Favale F, Messaoudi K, Varghese L, Boukour S, Pecquet C, Gryshkova V, et al.
Blood
. 2016 Dec;
128(26):3146-3158.
PMID: 28034873
The mechanisms behind the hereditary thrombocytosis induced by the thrombopoietin (THPO) receptor MPL P106L mutant remain unknown. A complete trafficking defect to the cell surface has been reported, suggesting either...
10.
Tanzer M, Tripaydonis A, Webb A, Young S, Varghese L, Hall C, et al.
Biochem J
. 2015 Aug;
471(2):255-65.
PMID: 26283547
The pseudokinase MLKL (mixed lineage kinase domain-like), has recently emerged as a critical component of the necroptosis cell death pathway. Although it is clear that phosphorylation of the activation loop...